Improving Frailty With a Rigorous Ambulation Intervention in Lung Transplant Patients (iFRAIL)
Transplant-Related Disorder, Frail Elderly Syndrome, Sarcopenia
About this trial
This is an interventional prevention trial for Transplant-Related Disorder focused on measuring lung transplant, frailty
Eligibility Criteria
Inclusion Criteria:
Inclusion Criteria (pre-transplant):
- Participant has personally signed and dated informed consent form indicating understanding of all pertinent aspects of the study.
- Speaks fluent English
- Active on the waiting list for a single or bilateral lung transplant
- Able to ambulate pre-transplant (not bed/wheelchair bound) with or without assistive device
Inclusion Criteria (post-transplant)
- Have undergone a single or bilateral lung transplant
- Admitted to the transplant floor (J82) after discharge from the ICU
- Complete history and physical examination on file
- Physical therapy consult ordered (standard of care) and JH-HLM Scale of greater than or equal to 6 within 72 hours of transfer to the transplant floor
Exclusion Criteria (pre-transplant):
- Age <18 years
- Admitted to hospital for expedited transplant work-up
- Admitted to hospital prior to date of transplant
- Current invasive mechanical ventilation or placement of ECMO cannula
- Multi-organ transplant patients (liver-lung, heart-lung)
Exclusion Criteria (post-transplant)
- Bed rest order placed
- Requiring invasive mechanical ventilation during the day/night
Sites / Locations
- Cleveland Clinic
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Ambulatory Intervention
No Ambulator
Patients who score greater than or equal to 6 on the John's Hopkins Highest Level of Mobility (JH-HLM) scale, up to 72 hours after transfer from the ICU to the regular nursing floor will be enrolled in an ambulatory intervention. Care technicians will ambulate patients three times per day at their level of physical ability. They will also receive physical therapy standard of care.
Patients who score less than 6 on the John's Hopkins Highest Level of Mobility (JH-HLM) scale, up to 72 hours after transfer from the ICU to the regular nursing floor will not be enrolled in the ambulatory intervention. They will receive physical therapy standard of care.