Heart Inflammation and Mental Stress Study (HIMS)
Hypertension
About this trial
This is an interventional basic science trial for Hypertension focused on measuring High blood pressure, HIV
Eligibility Criteria
Inclusion criteria:
- pre-hypertension screening.
- HIV-antibody testing.
Exclusion criteria:
- current use of anti-lipid, antihypertensive, or heart rate altering medications;
- current or lifetime history of cardiovascular disease diagnosis or treatment including pulmonary stenosis, heart valve abnormalities and hypertension;
- current or lifetime diagnoses of cancer, kidney/liver disease, hypertension, Type 1 or Type 2 diabetes;
- history of trauma, cerebral infarction or hemorrhage;
- current diagnosis and/or treatment for hypertension;
- severe cognitive impairment;
- current treatment or diagnosis of psychiatric illness;
- metal implants or debris within the body; or pregnancy;
- body mass index > 35;
- use of hormone replacement therapy; and current smoker.
Sites / Locations
- University of MiamiRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
No Intervention
Paced breathing
Relaxing music
No intervention
Individuals will be asked to sit in a quiet room while sensors collect their heart rate, respiratory rate and blood pressure for approximately 45 minutes. Individuals in this arm will engage in a paced breathing. Initial respiratory rate will be measured with a transducer. Participants will be connected to a paced breathing device (RESPERATE) that will gradually reduce the pace of audio tones presented to those individuals from spontaneous breathing rate down to 6 - 8 breaths per minute.
Individuals will be asked to sit in a quiet room while sensors collect their heart rate, respiratory rate and blood pressure for approximately 45 minutes. Individuals will be provided with an audio device that plays soothing/relaxing music at a similar range (beats per minute) of the auditory signal presented during the experimental condition. Subjects will not be instructed how to breathe in this arm.
Individuals will be asked to sit in a quiet room while sensors collect their heart rate, respiratory rate and blood pressure for approximately 45 minutes.