Precision Diets for Diabetes Prevention
Pre Diabetes, Insulin Resistance
About this trial
This is an interventional prevention trial for Pre Diabetes
Eligibility Criteria
Inclusion Criteria:
- Be 18 years of age or older;
- Not be pregnant, if female;
Exclusion Criteria:
- Have major organ disease, hypertension defined as >160/100, pregnant/lactating, diabetogenic medications, malabsorptive disorders like celiac sprue, others, heavy alcohol use, use of weight loss medications or specific diets, weight change > 2 kg in the last three weeks, history of bariatric surgery.
- Any medical condition that physicians believe would interfere with study participation or evaluation of results.
- Mental incapacity a nd/or cognitive impairment on the part of the patient that would preclude adequate understanding of, or cooperation with, the study protocol.
Sites / Locations
- Stanford UniversityRecruiting
Arms of the Study
Arm 1
Other
Optimizing Diet for Glycemic Control
All individuals will go through all the phases of the study. Phase 1: Metabolic testing to determine insulin resistance status. Phase 2: Participants follow their own diet while using the CGM (continuous glucose monitor). Participants are provided with 5-10 standardized foods to test during this phase. Phase 3: Participants are provided with additional standardized foods and counseled to continue their own diet during this phase. Phase 4: Participants are counseled on reducing or limiting the foods that caused glucose spikes and they are also counseled on macronutrient composition of their diet based on lipid profile. Participants use the CGM for another cycle of 2-3 weeks to assess effectiveness of the recommendations. Blood is drawn for analyses before and after this cycle.