Neuromuscular Plasticity in Response to Obesity: Effects of Mechanical Overload, Metabolic Disorders and Age (PLANEUROB)
Obesity
About this trial
This is an interventional other trial for Obesity focused on measuring Obese, Torque production, Neuromuscular fatigue, Electrical muscle stimulation, Knee extensors, Metabolic disorders
Eligibility Criteria
Inclusion Criteria:
- Female or male subject, aged between 20 and 70 years old (inclusive terminals).
- Subject with a BMI greater than 30kg/m².
- Subject with a stable weight for at least 3 months before the start of the study.
- Subject capable and willing to comply with the protocol and willing to give informed consent in writing.
- Subject affiliated to a social security system.
Exclusion Criteria:
Subject with a medical or surgical history deemed by the investigator to be incompatible with the study.
- Subject with a medical contraindication to intense activity.
- Subject weighing more than 170kg, which may damage the dynamometer chair.
- Subject with a treatment that, in the investigator's opinion, may interfere with the evaluation of study criteria, period of exclusion from a previous clinical study.
- Subject who has received a total amount of compensation since the beginning of the calendar year, greater than 4500 euros (amount may change depending on the regulation).
- Subject with a linguistic or physiological disability to sign informed consent.
- Subject deprived of liberty by administrative of juridical decision, under guardianship or curatorship.
- Pregnant or breastfeeding women.
Sites / Locations
- Chu Clermont Ferrand
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
YOMH
YOMD
MAOMH
MAOMD
EOMH
EOMD
Young obese metabolically healthy Description: Aged from 20 to 40 years old and with a glycemia < 1g/l and a triglyceridemia < 1,5g/l.
Young obese with metabolic disorders Description: Aged from 20 to 40 years old and with a glycemia > 1g/l and a triglyceridemia > 1,5g/l.
Middle-Age obese metabolically healthy Description: Aged from 40 to 50 years old and with a glycemia < 1g/l and a triglyceridemia < 1,5g/l.
Middle-Age obese with metabolic disorders Description: Aged from 40 to 50 years old and with a glycemia > 1g/l and a triglyceridemia > 1,5g/l.
Elderly obese metabolically healthy Description: Aged from 50 to 70 years old and with a glycemia < 1g/l and a triglyceridemia < 1,5g/l.
Elderly obese with metabolic disorders Description: Aged from 50 to 70 years old and with a glycemia > 1g/l and a triglyceridemia > 1,5g/l.