Dietary Intervention and Assessment of Obesity-related Gene Methylation Levels in Overweight Women
Obesity

About this trial
This is an interventional prevention trial for Obesity focused on measuring Epigenetic, Obesity, Diet, Folate, Monounsaturated fat
Eligibility Criteria
Inclusion Criteria:
- Adult women, aged between 20 and 59 years;
- Women with classification of overweight and obesity;
- Women who signed the informed consent form.
Exclusion Criteria:
- Women who changed their lifestyle 3 months before the study started;
- Alcoholic women or smokers;
- Taking medications known to interfere with folic acid metabolism (in the past 3 months), such as antacids and anticonvulsants;
- Individuals who use supplements in general, such as fish oil or other fatty acids;
- Pregnant or planning to become pregnant during the study period.
Sites / Locations
- Raquel Patrícia Ataíde Lima
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Placebo Comparator
Experimental
No Intervention
Group 1: Folate + hazelnut oil
Group 2: Folate
Group 3: Moderate folate + hazelnut oil
Group 4: Control
Group 1 = in this group, the individuals received, during the period of 08 weeks daily, daily dietary intervention with, 300 g of vegetables rich in folate - 191µg and additionally received 01 capsule containing 25 mg hazelnut oil per day.
Group 2 = in this group, the individuals received, during the period of 08 weeks daily, daily dietary intervention with, 300 g of folate-rich vegetables - 191 µg and 01 placebo capsule.
Group 3 = in this group, individuals received, during the period of 08 weeks daily, with 300 g of vegetables containing 94 µg of folate and 01 capsule containing 25 mg of hazelnut oil per day.
Group 4 = in this group, individuals received weekly visits during the 08 week period to maintain their eating habits.