Effects of Low-Level Laser Therapy on Oxidative Stress Levels...
Hashimoto Thyroiditis, Autoimmune Thyroiditis, Thyroiditis
About this trial
This is an interventional treatment trial for Hashimoto Thyroiditis focused on measuring Hashimoto Thyroiditis, Oxidative Stress, Low-Level Laser Therapy, Fatigue, Quality of Life, Autoimmune Thyroiditis, Depression, Sleep, Anxiety, Thyroid Hormones, Photobiomodulation Therapy
Eligibility Criteria
Inclusion Criteria:
Cases between the ages of 18-65 who applied to the Kosuyolu Istanbul Medipol Hospital Endocrinology and Metabolic Diseases Clinic between 2020-2021 and diagnosed as "Hashimoto Thyroiditis" by a specialist physician will be included in the study.
Exclusion Criteria:
- Acute infection
- Use of immunosuppressants, immunostimulants and drugs that interfere with the production, transport, and metabolism of thyroid hormones
- Thyroid nodules
- Tracheal stenosis
- Serious illness
- History of exposure to ionizing radiation and/or neoplasia in the cervical region
- Malignancy and a history of thyroid surgery
- Hypothyrodism caused by postpartum thyroiditis
- Pregnancy and breastfeeding period
- Identification and diagnosis of the cases with neurological and psychiatric disorders.
Sites / Locations
- Sumeyye TUNC
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Low-level laser therapy group
Sham Group
Low Level Laser Therapy (LLLT): Low-level laser therapy will be applied to the cases in addition to LT4 hormone replacement therapy. LLLT group will be treated using a continuous wave GaAIAs type diode laser (Intelect® Mobile Laser, Model No: 2779, Production Year: 2016; Chattanooga Group) device in the treatment area of 0.07 cm2. Continuous mode at 850 nm wavelength, 100 mW output power,1.43 W/cm2 power density and 28.57 J / cm2 energy density will be used.
Probes were placed in the sham laser group in a similar way as in the treatment group. The screen of the laser device was active; however, the energy was set as 0 J and the power as 0 mW , respectively,and the same operations were also performed.