Satiation Study With Children Attending a Tertiary Feeding Clinic
Undernutrition, Underweight
About this trial
This is an interventional basic science trial for Undernutrition
Eligibility Criteria
Inclusion Criteria:
- Currently attending Glasgow Feeding Clinic or seen within the last 2 years.
- Completed ICFET questionnaire and eating solid food at least weekly.
- Body mass index < 9th centile.
- Within 40 minutes car travel from study centre
Exclusion Criteria:
- Patient or family member shielding from COVID.
- Not able to swallow safely
- Not taking solid foods
- Fully tube fed: i.e. receiving more than 75% of energy requirements from tube feeding.
No measurements
Sites / Locations
- New Lister building, Royal Infirmary
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
High energy
Low energy
Child will be given a high energy drink: a flavoured high energy milk or juice-based drink, used clinically to supplement the diet of preschool children (either Pediasure plus or Duocal). This will provide 1.5 kcals per ml in various flavours as preferred. The amount given will supply 10% of the child's daily energy requirements per Kg - for example for a 2-year-old child weighing 15 KG this would be 80 mls of drink supplying 120 Kcal. They will be given 10 minutes to drink the preload and 30 minutes after this they will eat lunch containing a range of pre-packaged foods of known energy content suitable for their age, chosen in consultation with the parents.
Child will be given a low energy drink of the same volume selected to be as similar as possible to the high energy drink, made either of skim milk or sugar free fruit juice, with a similar sugar free flavour; for above example this will supply 25 kcal. They will be given 10 minutes to drink the preload and 30 minutes after this they will eat lunch containing the same range of pre-packaged foods as above.