Oral Prophylactic Measures on the Occurrence of Pre-eclampsia (OP-PE) (OP-PE)
Pregnancy Complications
About this trial
This is an interventional prevention trial for Pregnancy Complications focused on measuring pre-eclampsia, pregnant, periodontal disease, interdental microbiota
Eligibility Criteria
Inclusion Criteria:
- pregnant woman
- women from sub-Saharan Africa
- aged from 18 to 35 years old
- nullipares at the time of the obstetrical consultation
- up to 12 weeks pregnant
- acceptance of the terms and conditions of the study
- signature of the informed consent form,
Exclusion Criteria:
- fetal distress
- congenital uterine and vaginal abnormalities
- infectious or systemic diseases such as HIV, tuberculosis, candidiasis, cancers, hemopathies
- premature termination of pregnancy for medical reasons
- periodontal lesions of stage II, III (i.e., PD ≥ 4 mm, and/or CAL ≥ 4 mm), generalized (>30% of sites)
- history or treatment of PD
- a course of dental or orthodontic treatment
- less than 20 natural teeth, excluding third molars
- medication affecting the gum and/or oral mucosa
- regularly using interdental brushes and/or dental floss and/or mouthwash
- unable to answer questions or non-cooperative.
Sites / Locations
- HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Control group
Oral prophylactic intervention
The control group will continue its usual oral hygiene practice.
For the study group, the oral prophylactic intervention will consist of provision of specfic package including soft-bristled manual toothbrush, toothpaste, and a kit of calibrated interdental brushes (IDBs)(Curaprox CPS; Curaden) of sizes corresponding to the diameter of their interdental spaces. The participants will be instructed to brush their teeeth twice-daily and to realise a daily interdental brushing until delivery. The instructions for the use of the toothbrush and IDBs comprised verbal instructions supported by practical demonstration. The first use of the material will be conducted under the supervision of a qualified public health professor.