Study on the Effect of Two Ways of Cycloplegia on Biological Parameters of Ciliary Muscle
Accomodation, Refractive Errors, Myopia
About this trial
This is an interventional diagnostic trial for Accomodation
Eligibility Criteria
Inclusion Criteria:
①Age 6 to 12 years old;
Both eyes are in line with the diagnosis of myopic refractive error and the myopia is 0.25D < myopia spherical lens <6.00D, astigmatism <2.00D, binocular anisometropia <3.00D, and the best corrected distance visual acuity is at least 0.8, near vision at least 0.8;
A clear anterior segment image can be obtained through anterior segment OCT;
- Have normal thinking and language communication skills, and can actively cooperate with the inspection process; ⑤ No contraindications to atropine treatment such as acute eye inflammation, dry eye, keratoconus, diabetes, etc.; ⑥Written informed consent of the guardian and the child himself
Exclusion Criteria:
① Combined with neurological diseases and have allergies or contraindications to cycloplegic drugs or other drugs;
Intraocular pressure ≥21mmHg; history of photosensitivity, glaucoma, blue eye syndrome, ocular hypertension, and retinal macular lesions or damage;
Patients with chronic eye diseases such as ocular trauma and allergic conjunctivitis;
Those who wear contact lenses and those who use myopia control-related drugs within 1 month; ⑤ Patients with previous varus trichiasis, severe horn, conjunctiva infection and other eye diseases;
Insufficient image quality, such as inconsistent field of view, poor image exposure, inaccurate image focus, stains, shadows or crescent shadows, etc.;
- There are systemic diseases; ⑧ Epilepsy, mental disorders unable to communicate normally; ⑨ Other circumstances judged by the investigator to be unsuitable to participate in the research
Sites / Locations
- Shanghai Eye Diseases Prevention & Treatment CenterRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
1% atropine
tropicamide
1% atropine eye drops, in the conjunctival sac, once a night, for 7 days
tropicamide eye drops, in the conjunctival sac, once every 5 minutes, after 3 consecutive doses, close eyes for 20 minutes