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Active clinical trials for "Myopia"

Results 1-10 of 694

Efficacy of Repeated Low-level Red-light Therapy in Myopia Control

Myopia

Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of exposure to induce the myopia control effect. The efficacy of the low-level red-light technology has been proven in a Chinese population. This trial demonstrated that 3-minutes per session twice a day repeated low-level red-light treatment controlled 87.7% of refraction progression and 76.8% of axial length elongation when the time of compliance to the treatment was 75%. Repeating this RCT in culturally diverse groups will confirm and translate this technology into a solution for myopia control globally.

Recruiting16 enrollment criteria

Clinical Study of PAL-222 Targeting Patients With Myopic Chorioretinal Atrophy (PAMyCA)

Myopic Chorioretinal Atrophy

The goal of this clinical trial is to assess efficacy and safety in patients with myopic chorioretinal atrophy. The main question it aims to answer are: • Percentage of changes in the chorioretinal atrophic area Participants will be implanted one sheet of PAL-222 into the subretinal space through pars plana vitrectomy. Researchers will compare non-therapeutic eye to see if the changes is significant different.

Recruiting22 enrollment criteria

Efficacy and Safety of 1% Atropine "5+3" Regimen in Children and Adolescents Controlling Myopia...

Myopia

Studies have shown that atropine eye drops are effective in controlling myopia in children and adolescents. 1% atropine ophthalmic drug has obvious curative effect for controlling myopia, but its side effects such as photophobia and blurred vision limit its popularization and use. In the early stage, our research group used 1% atropine "5+3" myopia control program and 1% atropine alternate eye myopia control program. Retrospective clinical research data showed that it could significantly reduce side effects and improve use compliance, but there is currently no evidence from prospective clinical studies.

Recruiting12 enrollment criteria

3D Visualization System for Vitreoretinal Diseases in Highly Myopic Eyes

Patients With Highly Myopic Eyes

To investigate the surgical outcomes and intraoperative parameters evaluation of 3D visualization system for vitreoretinal diseases in highly myopic eyes

Recruiting6 enrollment criteria

MiSight 1 Day Safety Post-Approval Study

Myopia

The purpose of this post-approval study is to confirm the safety of daily disposable soft contact lens wear among the intended patient population for the MiSight 1 Day lens in the US.

Recruiting20 enrollment criteria

Effects of Different Designs of Orthokeratology Lens on Myopia Control and Visual Quality

Myopic Progression

This study was aimed to evaluate the effects of different Orthokeratology,including the size of central optical zone and the height of peripheral reverse curve, on myopia control and visual quality.

Recruiting9 enrollment criteria

Defocus (DIMS) Spectacles Versus Ortho-K Lenses (OKL) for Slowing Myopia Progression in Danish Children...

Myopia

The purpose is to compare the myopia control efficacy of Ortho-K lenses (OKL) and Defocus (DIMS) spectacles in Danish myopic children aged 6-12 years. It is a clinical randomized non-inferiority trial, where the participants are randomly assigned to either OKL or DIMS spectacles. The participants are followed during 18 months of therapy. The hypotheses: There is no statistically significant difference between the myopia control efficacy between OKL and DIMS spectacles. Larger pupil size is positively correlated to treatment efficacy for both devises. Increasing choroidal thickness during early treatment is positively correlated to treatment efficacy for both devises. There is no difference in vision related quality of life between the two groups.

Recruiting8 enrollment criteria

Low-dose Atropine for Myopia Control in Children

MyopiaProgressive

Myopia (nearsightedness) is the most common eye disorder. Only second to age, it is the main risk factor for major degenerative eye diseases such as glaucoma, macular degeneration or retinal detachment. Their risk increases with the degree of myopia. Hence, prevention of myopia and slowing its progression is of high relevance. Almost all clinical studies, including two large randomised clinical trials (RCT) were performed in Asia with Asian study participants. The results indicate that atropine eye drops can attenuate myopic progression in children, even in low concentrations thus minimizing unwanted side effects. However, the cumulative evidence is yet not strong enough to recommend their unrestricted use, especially in a Non-Asian population. We therefore intend to set up an adequately powered RCT comparing atropine 0.02% eye drops with placebo to validate previous findings and to test whether this therapeutic concept holds its promise in a European population.

Recruiting24 enrollment criteria

Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)

Myopia

The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.

Recruiting23 enrollment criteria

SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense)

MyopiaAstigmatism

The Use of the VisuMaxTM Femtosecond Laser Small-Incision Lenticule Extraction (SMILE) Procedure for the Correction of Myopia with or without Astigmatism study is a prospective, non-randomized, multicenter clinical study that will be conducted by the Navy Refractive Surgery Center, Naval Medical Center San Diego, CA in collaboration with the U.S. Air Force 59th Medical Wing, Wilford Hall Eye Center, TX, and the U.S. Army Warfighter Refractive Eye Surgery Program and Research Center, Fort Belvoir Community Hospital, VA.

Recruiting38 enrollment criteria
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