Comparative Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients
Primary Purpose
Parkinson Disease, Balance; Distorted, Postural; Defect
Status
Completed
Phase
Not Applicable
Locations
Pakistan
Study Type
Interventional
Intervention
cognitive training and conventional training
motor dual task training along with conventional therapy
Sponsored by
About this trial
This is an interventional treatment trial for Parkinson Disease focused on measuring Parkinson Disease, Balance; Distorted, Postural; Defect
Eligibility Criteria
Inclusion Criteria:
- A stage I-II-III Hoehn and Yahr scale consultant neurologist's diagnosis of Parkinson's disease
- A stable medication schedule both before and during the trial period
- can walk without assistive aid
Exclusion Criteria:
- Other neurological conditions in additions to Parkinson's disease such as CVA, Head injuries, Trauma
- Any Musculoskeletal condition e.g., total knee replacement surgery and rheumatoid arthritis
- Sensory impairments (vestibular dysfunctions)
Sites / Locations
- Riphah International University
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
experimental group
control group
Arm Description
cognitive training and conventional training
motor dual task training and conventional training
Outcomes
Primary Outcome Measures
time up and go test
In time up and go test instruct patient stand up and then walking 3 meters far then rotate and come back. Therapist noted the whole procedure time
Parkinson Disease Questionnaire-39 (PDQ-39).
Parkinson Disease Questionnaire-39 (PDQ-39).The tool carried out 39 items. The tool carried out 39 items. For each domain, five answer shows that every part score is 0 (good) to 100 (critical). Decreased scores showed better quality of life
Secondary Outcome Measures
Full Information
NCT ID
NCT05506813
First Posted
August 17, 2022
Last Updated
November 8, 2022
Sponsor
Riphah International University
1. Study Identification
Unique Protocol Identification Number
NCT05506813
Brief Title
Comparative Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients
Official Title
Comparative Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients
Study Type
Interventional
2. Study Status
Record Verification Date
November 2022
Overall Recruitment Status
Completed
Study Start Date
January 1, 2022 (Actual)
Primary Completion Date
August 20, 2022 (Actual)
Study Completion Date
August 20, 2022 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Riphah International University
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
To Compare Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients
Detailed Description
This study will be conducted to compare the Comparative Effect of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients. total 20 Patients will be recruited according to the inclusion criteria and data will be collected from the Riphah Rehabilitation center Lahore, Muhammadi Medical trust hospital Lahore. Time Up and Go test (TUG) Parkinsons disease Questionnaire 39 (PDQ-39) will be used as data collection tool. To assess the balance and quality of life in parkinson's patients. Patients will be allocated to intervention group by randomization. After approval from ethical committee, data collection will be started and informed consent will be taken from all patients
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Parkinson Disease, Balance; Distorted, Postural; Defect
Keywords
Parkinson Disease, Balance; Distorted, Postural; Defect
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Model Description
total 20 Participants will be divided in two groups. In group A patients will receive cognitive training along with conventional therapy. while in Group B Participants will receive motor dual task training along with conventional therapy.
Masking
None (Open Label)
Allocation
Randomized
Enrollment
20 (Actual)
8. Arms, Groups, and Interventions
Arm Title
experimental group
Arm Type
Experimental
Arm Description
cognitive training and conventional training
Arm Title
control group
Arm Type
Active Comparator
Arm Description
motor dual task training and conventional training
Intervention Type
Other
Intervention Name(s)
cognitive training and conventional training
Intervention Description
cognitive training along with conventional therapy
Intervention Type
Other
Intervention Name(s)
motor dual task training along with conventional therapy
Intervention Description
motor dual task training along with conventional therapy
Primary Outcome Measure Information:
Title
time up and go test
Description
In time up and go test instruct patient stand up and then walking 3 meters far then rotate and come back. Therapist noted the whole procedure time
Time Frame
9 months
Title
Parkinson Disease Questionnaire-39 (PDQ-39).
Description
Parkinson Disease Questionnaire-39 (PDQ-39).The tool carried out 39 items. The tool carried out 39 items. For each domain, five answer shows that every part score is 0 (good) to 100 (critical). Decreased scores showed better quality of life
Time Frame
9 months
10. Eligibility
Sex
All
Minimum Age & Unit of Time
50 Years
Maximum Age & Unit of Time
75 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
A stage I-II-III Hoehn and Yahr scale consultant neurologist's diagnosis of Parkinson's disease
A stable medication schedule both before and during the trial period
can walk without assistive aid
Exclusion Criteria:
Other neurological conditions in additions to Parkinson's disease such as CVA, Head injuries, Trauma
Any Musculoskeletal condition e.g., total knee replacement surgery and rheumatoid arthritis
Sensory impairments (vestibular dysfunctions)
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Zeest Hashmi, MSNMPT
Organizational Affiliation
Riphah International University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Riphah International University
City
Islamabad
State/Province
Fedral
ZIP/Postal Code
44000
Country
Pakistan
12. IPD Sharing Statement
Plan to Share IPD
No
Citations:
PubMed Identifier
33595777
Citation
Bordignon A, Devita M, Sergi G, Coin A. "Cerebellar cognitive reserve": a possible further area of investigation. Aging Clin Exp Res. 2021 Oct;33(10):2883-2886. doi: 10.1007/s40520-021-01795-1. Epub 2021 Feb 17. No abstract available.
Results Reference
background
PubMed Identifier
33150515
Citation
Onder H, Ozyurek O. The impact of distinct cognitive dual-tasks on gait in Parkinson's disease and the associations with the clinical features of Parkinson's disease. Neurol Sci. 2021 Jul;42(7):2775-2783. doi: 10.1007/s10072-020-04874-9. Epub 2020 Nov 4.
Results Reference
background
PubMed Identifier
33160824
Citation
Bouscary A, Quessada C, Rene F, Spedding M, Turner BJ, Henriques A, Ngo ST, Loeffler JP. Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. Semin Cell Dev Biol. 2021 Apr;112:82-91. doi: 10.1016/j.semcdb.2020.10.008. Epub 2020 Nov 5.
Results Reference
background
Learn more about this trial
Comparative Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients
We'll reach out to this number within 24 hrs