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Improvement of Urinary Retention Symptoms With Electroacupuncture Therapy

Primary Purpose

Urinary Retention

Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
true electroacupuncture
sham electroacupuncture
Sponsored by
Indonesia University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Urinary Retention focused on measuring Urinary Retention, Postpartum urinary retention, electroacupuncture, vaginal delivery, acupuncture

Eligibility Criteria

20 Years - 40 Years (Adult)FemaleAccepts Healthy Volunteers

Inclusion Criteria:

  • subject who had urinary retention 6 hours after vaginal delivery and the residual urine volume 500 - 1000 mL
  • female 20 - 40 years old
  • pregnancy > 34 weeks and baby's weight > 2000 gr
  • agree to participate in this study and sign the inform consent

Exclusion Criteria:

  • patient who had emergency situation, such as bleeding or unstable hemodynamic
  • using pace maker
  • had cardiac arrhythmia
  • patient had disease that make them using the catheter (such as chronic kidney disease)
  • allergy to stainless steel
  • scar in the acupuncture point locations
  • using prothesis
  • had intrathecal labour analgesia (ILA)

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm Type

    Experimental

    Sham Comparator

    Arm Label

    True electroacupuncture group

    sham electroacupuncture group

    Arm Description

    the investigators use stainless steel acupuncture needle, disposable : Huanqiu® 0.25 x 0.40 mm Electroacupuncture device : Hwato-SDZ V®, continuous wave, 2 Hz, for 30 minutes

    the investigators use the same device like true electroacupuncture group, but the acupuncture needle not puncture on the skin and only attached. electroacupuncture device, with no electrical stimulation

    Outcomes

    Primary Outcome Measures

    residual urine volume after electroacupuncture therapy and catheter removal
    after 24 hours using catheter, it will be remove. 6 hours after catheter removal, the investigators will check how much the residual urine volume in the bladder

    Secondary Outcome Measures

    first time micturation
    after 24 hours using catheter, it will be remove. anytime after the removal if participants going to first micturition, the investigators will collect the data

    Full Information

    First Posted
    August 28, 2022
    Last Updated
    September 2, 2022
    Sponsor
    Indonesia University
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    1. Study Identification

    Unique Protocol Identification Number
    NCT05526651
    Brief Title
    Improvement of Urinary Retention Symptoms With Electroacupuncture Therapy
    Official Title
    Improvement of Urinary Retention Symptoms After Vaginal Delivery With Electroacupuncture Therapy
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    September 2022
    Overall Recruitment Status
    Not yet recruiting
    Study Start Date
    August 31, 2022 (Anticipated)
    Primary Completion Date
    December 12, 2022 (Anticipated)
    Study Completion Date
    December 12, 2022 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    Indonesia University

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No
    Data Monitoring Committee
    Yes

    5. Study Description

    Brief Summary
    Postpartum urinary retention (PPUR) can occur in women who deliver vaginally. The incidence of this occurrence varies from 1.7 - 17.9%, this different variation due to different definitions of PPUR and the methods used to measure it. There are 2 categories of RUPP, namely covert and overt, in overt PPUR the prevalence ranges from 0.3 to 4.7%, while covert PPUR can reach up to 45%. In Indonesia alone, the incidence of PPUR is around 14.8%3, where vaginal PPUR is around 70% more higher than sectio caesarean patients. A study conducted at the RSCM in 2009 by Yustini, et al stated that the incidence of PPUR was 9-14%, and if the delivery was using forceps it would increase to 38%. Other studies conducted by Suskhan at the RSCM in 2015, it was stated that the incidence of urinary retention was 13.6% of 500 research subjects. Another study conducted by Chen, et al in 2020 in China, stated that the most common cause of urinary retention in hospitals was surgery. gynecological cases, which is 69% while for obstetric cases by 18.6% where the main cause of this retention is due to vaginal delivery. The high number of PPUR can increase the incidence of postpartum hemorrhage, urinary tract infections, mental fatigue during the puerperium and result in delays in breastfeeding. Bladder catheterization which is one of the treatments for PPUR is also closely related to the risk the occurrence of morbidity and complications, where 17.5% of urinary tract infections are infections obtained from hospitals or HAIs (Healthcare Associated Infections) and 80% of these infections are caused by the installation of urethral catheters, especially the installation of urethral catheters in the ER which is carried out without clear indications such as described in a study conducted by Gokula et al in Michigan in 2007. According to Sudhakaran, symptomatic RUPP (overt) is defined as the absence of a spontaneous voiding process or the inability to urinate since 6 hours after vaginal delivery or 6 hours after catheter removal after caesarean section. Asymptomatic (covert) PPUR is defined as a post-void residual volume (PVRV) 200 ml after the first spontaneous urination as measured by ultrasound or catheter, which indicates incomplete voiding.6 Asymptomatic PPUR may occur due to reduced sensation and contractility that occurs as a result of trauma from the innervation to the bladder. Symptoms of this RUPP according to Suskhan are unexplained urination, prolonged urination, more frequent urination, inability to urinate, feeling of full bladder and abdominal distension. The presence of the above symptoms will cause the bladder to enlarge during a physical examination of the abdomen. Acupuncture as a non-medical therapy has been widely used both in China and in other countries, especially to treat pain and neurological disorders. Urination is a neural reflex activity. Acupuncture points that correspond to the innervation of the bladder can stimulate conduction of parasympathetic nerve impulses, resulting in bladder detrusor contraction, increased intravesical pressure and relaxation of the internal sphincter. Thus, acupuncture can regulate bladder function in the process of urination. Based on the study of Zhao, et al, it was stated that electroacupuncture can stimulate afferent and efferent nerves in the pelvic cavity of rats, increase detrusor contraction and encourage urination. Other studies have shown that electroacupuncture can also reduce the myoelectric activity of abnormal contraction of the external urethral sphincter during urination, reduce resistance during urination, improve coordination between the bladder detrusor and urethral sphincter and reduce residual urine volume. As for the side effects caused by acupuncture based on a systematic study conducted almost none. Based on the description above, acupuncture can be considered as a supportive therapy that can overcome the problem of PPUR with minimal side effects to prevent worsening of the condition. In this study, researchers wanted to determine the effectiveness of acupuncture interventions using electroacupuncture modalities to accelerate urination after delivery and reduce residual urine volume in patients after vaginal delivery with electroacupuncture intervention for 30 minutes / session, 2 sessions in 1 x 24 hours.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Urinary Retention
    Keywords
    Urinary Retention, Postpartum urinary retention, electroacupuncture, vaginal delivery, acupuncture

    7. Study Design

    Primary Purpose
    Treatment
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Model Description
    Study divided into 2 arms, true electroacupuncture group and sham electroacupuncture group
    Masking
    ParticipantCare ProviderOutcomes Assessor
    Allocation
    Randomized
    Enrollment
    60 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    True electroacupuncture group
    Arm Type
    Experimental
    Arm Description
    the investigators use stainless steel acupuncture needle, disposable : Huanqiu® 0.25 x 0.40 mm Electroacupuncture device : Hwato-SDZ V®, continuous wave, 2 Hz, for 30 minutes
    Arm Title
    sham electroacupuncture group
    Arm Type
    Sham Comparator
    Arm Description
    the investigators use the same device like true electroacupuncture group, but the acupuncture needle not puncture on the skin and only attached. electroacupuncture device, with no electrical stimulation
    Intervention Type
    Other
    Intervention Name(s)
    true electroacupuncture
    Intervention Description
    the investigators use stainless steel acupuncture needle, disposable : Huanqiu® 0.25 x 0.40 mm Electroacupuncture device : Hwato-SDZ V®, continuous wave, 2 Hz, for 30 minutes
    Intervention Type
    Other
    Intervention Name(s)
    sham electroacupuncture
    Intervention Description
    the investigators use the same device like true electroacupuncture group, but the acupuncture needle not puncture on the skin and only attached. electroacupuncture device, with no electrical stimulation
    Primary Outcome Measure Information:
    Title
    residual urine volume after electroacupuncture therapy and catheter removal
    Description
    after 24 hours using catheter, it will be remove. 6 hours after catheter removal, the investigators will check how much the residual urine volume in the bladder
    Time Frame
    6 hours
    Secondary Outcome Measure Information:
    Title
    first time micturation
    Description
    after 24 hours using catheter, it will be remove. anytime after the removal if participants going to first micturition, the investigators will collect the data
    Time Frame
    6 hours

    10. Eligibility

    Sex
    Female
    Minimum Age & Unit of Time
    20 Years
    Maximum Age & Unit of Time
    40 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: subject who had urinary retention 6 hours after vaginal delivery and the residual urine volume 500 - 1000 mL female 20 - 40 years old pregnancy > 34 weeks and baby's weight > 2000 gr agree to participate in this study and sign the inform consent Exclusion Criteria: patient who had emergency situation, such as bleeding or unstable hemodynamic using pace maker had cardiac arrhythmia patient had disease that make them using the catheter (such as chronic kidney disease) allergy to stainless steel scar in the acupuncture point locations using prothesis had intrathecal labour analgesia (ILA)
    Central Contact Person:
    First Name & Middle Initial & Last Name or Official Title & Degree
    Ayu Permata Sari, MD
    Phone
    082121070080
    Email
    apsari2489@gmail.com

    12. IPD Sharing Statement

    Plan to Share IPD
    Undecided

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    Improvement of Urinary Retention Symptoms With Electroacupuncture Therapy

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