Effect of the Nutritional Support System on Neuromotor Alterations in Patients With Cerebral Palsy (NSS-PC)
Cerebral Palsy, Spastic, Malnutrition
About this trial
This is an interventional treatment trial for Cerebral Palsy focused on measuring Cerebral Palsy, Nutritional Support, NSS, Probiotics, Diet, Neurogenesis, Neuroplasticity
Eligibility Criteria
Inclusion Criteria: Patients with GMFCS III classification. Patients with spastic CP. Both sexes age 4 to 11 years. Primary caregiver engaged (full presence). Able to follow instructions. Tolerant to oral feeding. Parents or guardians to sign informed consent letter. Children, if able to write, sign the letter of assent. Exclusion Criteria: Have received antibiotics 15 days prior to treatment. Having received botulinum toxin therapy in the last six months. Consumption of muscle relaxants in the last three months. Patient with any type of surgery in a period of less than 6 months. Presence of any other catabolic disease, which further increases their risk of malnutrition (renal, cardiovascular, pulmonary, hepatic, immunological). Intolerance to oral feeding. Lack of stimulation at home. Moderate to severe gastroesophageal reflux. Able to walk without support.
Sites / Locations
- Apac I.A.P. (Association For People With Cerebral Palsy)Recruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
No Intervention
Experimental
Experimental
FG (FOLLOW GROUP)
CG (CONTROL GROUP)
IG (INTERVENTION GROUP)
FG receive: Conventional diet (WHO).
CG receive: Conventional diet (WHO), deworming (nitazoxanide at a dosage of 7.5 mg / kg every 12 hours for 3 days), and probiotics (Saccharomyces Boulardii, 200 mg every 12 hours for 6 days at week 1, 5 and 9).
IG receive: Deworming (nitazoxanide at a dosage of 7.5 mg / kg every 12 hours for 3 days), probiotics (Saccharomyces Boulardii, 200 mg every 12 hours for 6 days at week 1, 5 and 9), specific diet, and NSS envelope (glutamine, arginine, folic acid, PUFA-n3, vegetal protein, nicotinic acid, cobalamin, thiamine, pyridoxine, magnesium, zinc, selenium, cholecalciferol, resveratrol, ascorbic acid, Spirulina Máxima, and inuline) every 12 hours for 12 weeks.