Functional Residual Capacity Under Apnoeic Oxygenation With Different Flow Rates in Children (FUTURE)
Apnea, Anesthesia, Intubation Complication
About this trial
This is an interventional prevention trial for Apnea focused on measuring Atelectasis, Apnoeic oxygenation, High-flow nasal oxygen, Silent spaces, Functional residual capacity, Paediatric anaesthesia
Eligibility Criteria
Inclusion Criteria: Written informed consent by legal guardian Paediatric patients undergoing elective surgery requiring general anaesthesia at the Bern University Hospital - Inselspital in Bern Child weight between 10-20kg American Society of Anesthesiology (ASA) physical status 1 & 2 (healthy child, no severe co-morbidities) Exclusion Criteria: Known or suspected difficult intubation Oxygen dependency Congenital heart or lung disease Obesity BMI (kg/m2) >30 High aspiration risk (requiring rapid sequence intubation).
Sites / Locations
- Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of BernRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Active Comparator
Experimental
Group 1: Low-flow apnoeic oxygenation
Group 2: High-flow apnoeic oxygenation
Group 3: Control group apnoeic oxygenation
Group 4: High-flow apnoeic oxygenation
Group 1) 0.2 L/kg/min using OptiFlow system by Fisher&Paykel and an oxygen inspiration concentration FiO2 of 1.0;
Group 2) 2 L/kg/min using OptiFlow system by Fisher&Paykel and an oxygen inspiration concentration FiO2 of 1.0;
Group 3) 4 L/kg/min using OptiFlow system by Fisher&Paykel and an oxygen inspiration concentration FiO2 of 1.0;
Group 4): 2 l/kg/min with OptiFlow FiO2 1.0 using OptiFlow-Switch system by Fisher&Paykel