Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 (REMA-CKD)
Kidney Diseases, Metabolic Acidosis, Renal Insufficiency
About this trial
This is an interventional treatment trial for Kidney Diseases focused on measuring Potential renal acid load, PRAL, Study design, Diet, Humans, Elderly, Bicarbonate/blood, Muscle strength, Hand strength, Chair stand test, Calorimetry, indirect, Bone mineralization, Carbon dioxide/blood, Phosphor/urine, Potassium/urine, Urea/blood, Urea/urine
Eligibility Criteria
Inclusion Criteria: Chronic acidosis (plasma-bicarbonate under 22 mmol/l at multiple measures within the last 12 months). Diagnosed with non-dialysis needed chronic kidney disease in stage 4 and 5 (eGFR below 30 ml/min/1,73 m2) Of legal age and over 18 of years Understand danish and understand the written material Able to cooperate about the diet Able to take pictures with their phone or willing to learn Exclusion Criteria: Vegan and vegetarian with very low intake of animal protein (below 25 g/day) Pregnant or breast feeding Patients with short bowel syndrome, bricker bladder, pancreatitis or any other known malabsorption problem Potassium above 5 mmol/l Ongoing infection
Sites / Locations
- Nordshjaellands HospitalRecruiting
Arms of the Study
Arm 1
Experimental
Low PRAL diet
Experimental: Low PRAL diet Crossover design: 1 arm consisting of three consecutive periods of two weeks (control, intervention and follow up).