Renasight Clinical Application, Review and Evaluation (RenaCARE) Study (RenaCARE)

Inclusion Criteria: Patients must meet all the following selection criteria to be eligible for the study. Eligibility will be assessed by the investigator: Male or female patients, age 18 years or older at the time of signing the informed consent form (ICF). If over the age of 65, patient must have a family history of CKD or clinical suspicion of genetic disorder. Able to read, understand, and provide written informed consent Willing and able to comply with the study-related procedures Diagnosis of kidney disease, and/or one of the following without any kidney biopsy (note: can be newly diagnosed or existing patient): Nephropathy associated with Diabetes Mellitus (DM)* Nephropathy associated with Hypertension* Cystic nephropathy* Congenital nephropathy Tubulointerstitial disease of unknown etiology Proteinuric disease suggestive of a primary glomerulopathy by clinical evaluation Early, severe or familial hypertension Thrombotic microangiopathy Electrolyte and acid base disorder Nephrolithiasis with family history CKD of unknown cause after standard nephrological evaluation End stage kidney disease (ESRD) *Total number of patients in each of these categories will not exceed 10% of total cohort Exclusion Criteria: Patients are not eligible for the study if they meet any of the following criteria, as assessed by the investigator: Age less than 18, or greater than 65 without a family history of CKD or clinical suspicion of genetic disorder History of renal transplant Clinical features and a kidney biopsy diagnosis strongly indicative of a secondary nephropathy (e.g., diabetic nephropathy, lupus nephritis, acute kidney injury) Previously confirmed diagnosis of a hereditary kidney disease via genetic testing.