Effect of a fNIRS-based Personalized Multi-domain Intervention on Cognitive in Elderly Population With High Risk of Stroke
Cognitive Impairment, Stroke, Dementia
About this trial
This is an interventional prevention trial for Cognitive Impairment
Eligibility Criteria
Inclusion Criteria: Aged 45-74 years high risk of stroke (with≥3 of 8 stroke risk factors, including hypertension, dyslipidemia, diabetes, atrial fibrillation or valvular heart disease, smoking history, obvious overweight or obesity, lack of exercise, family history of stroke, or with transient ischemic attack) Exclusion Criteria: previously diagnosed dementia previously diagnosed stroke (both cerebral infarction and hemorrhage) suspected dementia after clinical assessment by study physician at screening visit Mini-mental State Examination [MMSE] score<20 disorders affecting safe engagement in the intervention (e.g., malignant disease, major depression, symptomatic cardiovascular disease, revascularization within 1 year previously) severe loss of vision, hearing, or communicative ability disorders preventing cooperation as judged by the study physician coincident participation in another intervention trial any MRI contraindications
Sites / Locations
- Min Lou
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Standard health counseling
Personalized multidomain intervention