Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease
Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
About this trial
This is an interventional treatment trial for Mild Cognitive Impairment
Eligibility Criteria
Inclusion Criteria: Must be clinically diagnosed with PPA, FTD, MCI or mild AD. Diagnosis will be based on neuropsychological testing, language testing (most commonly the Western Aphasia Battery), MRI, and clinical assessment. Must be right-handed. Must be proficient in English. Must have a minimum high-school education. Exclusion Criteria: Uncorrected visual or hearing impairment by self-report. Stroke/other premorbid neurological disorder affecting the brain. Any other developmental language-based learning disorder other than PPA. Inability to follow directions for baseline tasks. Pre-existing psychiatric disorders such as behavioral disturbances, severe depression, and schizophrenia that do not allow them to comply or follow the study schedule and requirements such as repeated evaluation and therapy will be excluded. Exclusion Criteria for MRI participation: Severe claustrophobia. Cardiac pacemakers or ferromagnetic implants. Pregnant women.
Sites / Locations
- Johns Hopkins UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Active tDCS on the DLPFC + Cognitive Intervention(s)
Active tDCS on the DLPFC only
Participants will receive active tDCS on DLPFC + Cognitive Intervention(s) first and then receive only active tDCS Intervention after a three-month washout period.
Participants will receive active tDCS on the DLPFC-only intervention first and then receive active tDCS + Cognitive Intervention(s) after a three-month washout period.