Back to resultsAI-Assisted Treatment for Residual Speech Sound Disorders
Primary Purpose
Speech Sound Disorder
Status
Not yet recruiting
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Speech-Language Pathologist-led Speech Motor Chaining
Artificial Intelligence-led Speech Motor Chaining (CHAINING-AI)
Sponsored by
About this trial
This is an interventional treatment trial for Speech Sound Disorder
Eligibility Criteria
Inclusion Criteria: Must speak a rhotic dialect of American English as a dominant language. Must have begun learning English by at least the age of 3 years. Must be between 9;0 to 17;11 years of age. Must have reported difficulty with /ɹ/ production. Must have reported hearing within normal limits. Must receive a Scaled Score of 5 or above on both the Listening Comprehension and Story Retelling subtests from the Test of Integrated Language & Literacy Skills (TILLS). Must receive a percentile score of 8 or below on the Goldman-Fristoe Test of Articulation-3 (GFTA-3) Sounds in Words subtest. Must have 1 scorable response with 5+ consecutive correct /pataka/ with > 3.4 syllables per second in the MRR-Tri task of the Maximum Performance Tasks OR must demonstrate no childhood apraxia of speech (CAS-only) features in BOTH articulatory and rate/prosody domains of the ProCAD. Must score <40% accurate based on word-level items from our /ɹ/ probe list. Must score >=15% accuracy on /ɹ/ on 45 syllables following Dynamic Assessment. Must express interest in changing their /ɹ/ production. Must have oral structure and function that are appropriate for /ɹ/ production. Must have access to broadband internet with videoconferencing capabilities Exclusion Criteria: Must have no known history of autism spectrum disorder, Down Syndrome, cerebral palsy, intellectual disability, permanent hearing loss, epilepsy/antiepileptic medication, or brain injury/neurosurgery/stroke. Must not have diagnosis of attention deficit disorder, attention deficit hyperactivity disorder, Tourette's, or Obsessive-compulsive disorder. Must have no orthodontic appliances that block the roof of the mouth (e.g., palate expanders). Must not have current cleft palate, fluency disorder, or voice disorder. Must not demonstrate childhood apraxia of speech (CAS-only) features in BOTH articulatory and rate/prosody domains of the ProCAD.
Sites / Locations
- Syracuse University
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Experimental
Arm Label
CONCURRENT treatment order
SEQUENTIAL treatment order
Arm Description
5 speech lessons with a human speech-language clinician: 1 time per week for 5 weeks. 15 speech lessons with an AI clinician (supervised by the caregiver), 3 times per week DURING the same 5 weeks as the human clinician sessions.
5 speech lessons with a human speech-language clinician: 1 time per week for 5 weeks. 15 speech lessons with an AI clinician (supervised by the caregiver), 3 times per week for the 5 weeks AFTER the human clinician sessions end.
Outcomes
Primary Outcome Measures
Change in percent correct for the /ɹ/ sound in untreated words, rated by blinded listeners.
To assess generalization of treatment gains to untreated words, participants will read a word list eliciting /ɹ/. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy.
Secondary Outcome Measures
Retention of percent correct for the /ɹ/ sound in untreated words, rated by blinded listeners.
To assess generalization of treatment gains to untreated words, participants will read a word list eliciting /ɹ/. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. The timeframe of 10 weeks differs from the primary outcome of 5 weeks, and assesses longer-term retention and captures the effects after both groups have received both interventions.
Change in percent correct for the /ɹ/ sound in untreated words, rated by blinded listeners.
To assess generalization of treatment gains to untreated words, participants will read a word list eliciting /ɹ/. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. This timeframe compares the rate of improvement with Chaining-AI for the SEQUENTIAL group and the retention after a 5 week break for the CONCURRENT group.
Survey evaluating impacts of speech disorder on participants' social, emotional, and academic well-being.
This survey asks parents and participants to report the impact of speech disorder on their child's/their social, emotional, and academic well-being along a 5-point scale. A higher score indicates a greater degree of negative impact of speech disorder on social, emotional, or academic well-being.
Change in percent correct for the /ɹ/ sound in practiced words, rated by blinded listeners.
Participants will read word list eliciting /ɹ/ in practiced words to assess acquisition. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy.
Change in percent correct for the /ɹ/ sound in practiced words, rated by blinded listeners.
Participants will read word list eliciting /ɹ/ in practiced words to assess acquisition. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. The timeframe of 10 weeks captures longer-term retention of practiced words and captures the effects after both groups have received both interventions.
Change in percent correct for the /ɹ/ sound in practiced words, rated by blinded listeners.
Participants will read word list eliciting /ɹ/ in practiced words to assess acquisition. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. This timeframe compares the rate of improvement with Chaining-AI for the SEQUENTIAL group and the retention after a 5 week break for the CONCURRENT group.
Full Information
NCT ID
NCT05988515
First Posted
August 4, 2023
Last Updated
August 4, 2023
Sponsor
Syracuse University
Collaborators
National Institutes of Health (NIH), State University of New York - Upstate Medical University, National Institute on Deafness and Other Communication Disorders (NIDCD)
1. Study Identification
Unique Protocol Identification Number
NCT05988515
Brief Title
AI-Assisted Treatment for Residual Speech Sound Disorders
Official Title
AI-Assisted Treatment for Residual Speech Sound Disorders
Study Type
Interventional
2. Study Status
Record Verification Date
August 2023
Overall Recruitment Status
Not yet recruiting
Study Start Date
November 2023 (Anticipated)
Primary Completion Date
November 2027 (Anticipated)
Study Completion Date
December 2027 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Syracuse University
Collaborators
National Institutes of Health (NIH), State University of New York - Upstate Medical University, National Institute on Deafness and Other Communication Disorders (NIDCD)
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The goal of this randomized-controlled trial is to determine how artificial intelligence-assisted home practice may enhance speech learning of the "r" sound in school-age children with residual speech sound disorders. All child participants will receive 1 speech lesson per week, via telepractice, for 5 weeks with a human speech-language clinician. Some participants will receive 3 speech sessions per week with an Artificial Intelligence (AI)-clinician during the same 5 weeks as the human clinician sessions (CONCURRENT treatment order group), whereas others will receive 3 speech sessions per week with an AI-clinician after the human clinician sessions end (SEQUENTIAL treatment order group.
Detailed Description
Artificial Intelligence-assisted treatment that detects mispronunciations within an evidence-based motor learning framework could increase access to sufficiently intense, efficacious treatment despite provider shortages. A successful Artificial intelligencesystem that can predict the clinical gold standard of trained listeners' perceptions could not only improve access to clinical care but also mitigate known confounds to accurate clinical feedback, including clinical experience and drift due to increasing familiarity between the speaker and listener. The Artificial intelligence tool used in this study includes a speech classifier trained to predict clinician judgment of American English "r" that is integrated into an existing evidence-based treatment software called Speech Motor Chaining.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Speech Sound Disorder
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Model Description
Participants will be randomized across two conditions, CONCURRENT and SEQUENTIAL
Participants randomized to receive CONCURRENT treatment will receive speech lessons with a human clinician once per week for five weeks, along with 3 sessions per week of parent-supervised Chaining-AI (15 Chaining-AI sessions). Therefore, clinician-led and Chaining-AI are completed concurrently.
Participants randomized to receive SEQUENTIAL treatment will receive speech lessons with a human clinician once per week for five weeks, followed by three sessions per week of parent-supervised Chaining-AI for the NEXT five weeks. Therefore, clinician-led and Chaining-AI are completed sequentially.
Masking
Outcomes Assessor
Masking Description
All perceptual ratings will be obtained from trained listeners who are blinded to treatment group and to timepoint. Binary rating of accuracy of the "r" sound (i.e., judgments of correct or incorrect) will be obtained from three listeners per token.
Allocation
Randomized
Enrollment
26 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
CONCURRENT treatment order
Arm Type
Experimental
Arm Description
5 speech lessons with a human speech-language clinician: 1 time per week for 5 weeks.
15 speech lessons with an AI clinician (supervised by the caregiver), 3 times per week DURING the same 5 weeks as the human clinician sessions.
Arm Title
SEQUENTIAL treatment order
Arm Type
Experimental
Arm Description
5 speech lessons with a human speech-language clinician: 1 time per week for 5 weeks.
15 speech lessons with an AI clinician (supervised by the caregiver), 3 times per week for the 5 weeks AFTER the human clinician sessions end.
Intervention Type
Behavioral
Intervention Name(s)
Speech-Language Pathologist-led Speech Motor Chaining
Intervention Description
Sessions begin with Pre-practice to elicit the /r/ sound. During Structured Practice, the same utterance is practiced several times in a row (with systematic increases in difficulty based on performance). Our web-based software manipulates the principles of motor learning, including feedback prompts for the clinician, the complexity of the utterance, and the variability in the practice trial; the software will analyze the clinician's rating to increase the difficulty of practice when the child is more accurate. Randomized Practice will also be guided by the software and includes all linguistic levels that were produced correctly during Structured Practice, with items presented in random order. A trained speech-language pathologist is involved in all practice trials to provide feedback throughout the session.
Intervention Type
Behavioral
Intervention Name(s)
Artificial Intelligence-led Speech Motor Chaining (CHAINING-AI)
Intervention Description
Sessions include Structured Practice and Randomized Practice using our web-based software with an Artificial Intelligence clinician to address the /r/ sound. Within a practice session, participants speak into a microphone, and the audio file is sent to a server to be analyzed by a classifier, which returns a binary accurate/inaccurate rating of productions in a fashion similar to SLP judgment. Our web-based software manipulates the principles of motor learning, including feedback prompts, the complexity of the utterance, and the variability in the practice trial. The software will analyze the child's accuracy as determined by the classifier to increase the difficulty of practice when the child is more accurate.
Primary Outcome Measure Information:
Title
Change in percent correct for the /ɹ/ sound in untreated words, rated by blinded listeners.
Description
To assess generalization of treatment gains to untreated words, participants will read a word list eliciting /ɹ/. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy.
Time Frame
Before the initiation of treatment and again 5 weeks later.
Secondary Outcome Measure Information:
Title
Retention of percent correct for the /ɹ/ sound in untreated words, rated by blinded listeners.
Description
To assess generalization of treatment gains to untreated words, participants will read a word list eliciting /ɹ/. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. The timeframe of 10 weeks differs from the primary outcome of 5 weeks, and assesses longer-term retention and captures the effects after both groups have received both interventions.
Time Frame
Before the initiation of treatment and again 10 weeks later.
Title
Change in percent correct for the /ɹ/ sound in untreated words, rated by blinded listeners.
Description
To assess generalization of treatment gains to untreated words, participants will read a word list eliciting /ɹ/. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. This timeframe compares the rate of improvement with Chaining-AI for the SEQUENTIAL group and the retention after a 5 week break for the CONCURRENT group.
Time Frame
After 5 weeks of treatment and again 10 weeks later.
Title
Survey evaluating impacts of speech disorder on participants' social, emotional, and academic well-being.
Description
This survey asks parents and participants to report the impact of speech disorder on their child's/their social, emotional, and academic well-being along a 5-point scale. A higher score indicates a greater degree of negative impact of speech disorder on social, emotional, or academic well-being.
Time Frame
Before the initiation of treatment and again 5 weeks later.
Title
Change in percent correct for the /ɹ/ sound in practiced words, rated by blinded listeners.
Description
Participants will read word list eliciting /ɹ/ in practiced words to assess acquisition. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy.
Time Frame
Before the initiation of treatment and again 5 weeks later.
Title
Change in percent correct for the /ɹ/ sound in practiced words, rated by blinded listeners.
Description
Participants will read word list eliciting /ɹ/ in practiced words to assess acquisition. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. The timeframe of 10 weeks captures longer-term retention of practiced words and captures the effects after both groups have received both interventions.
Time Frame
Before the initiation of treatment and again 10 weeks later.
Title
Change in percent correct for the /ɹ/ sound in practiced words, rated by blinded listeners.
Description
Participants will read word list eliciting /ɹ/ in practiced words to assess acquisition. Stimuli in each list will be presented individually in randomized order. Individual words will be isolated from the audio record of each word probe and presented in randomized order for perceptual rating by trained listeners who are blind to treatment condition and time point (but will see the written representation of each target word). We will use the change in percent correct as our primary measure of perceptually rated accuracy. This timeframe compares the rate of improvement with Chaining-AI for the SEQUENTIAL group and the retention after a 5 week break for the CONCURRENT group.
Time Frame
After 5 weeks of treatment and again 10 weeks later.
10. Eligibility
Sex
All
Minimum Age & Unit of Time
9 Years
Maximum Age & Unit of Time
17 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Must speak a rhotic dialect of American English as a dominant language.
Must have begun learning English by at least the age of 3 years.
Must be between 9;0 to 17;11 years of age.
Must have reported difficulty with /ɹ/ production.
Must have reported hearing within normal limits.
Must receive a Scaled Score of 5 or above on both the Listening Comprehension and Story Retelling subtests from the Test of Integrated Language & Literacy Skills (TILLS).
Must receive a percentile score of 8 or below on the Goldman-Fristoe Test of Articulation-3 (GFTA-3) Sounds in Words subtest.
Must have 1 scorable response with 5+ consecutive correct /pataka/ with > 3.4 syllables per second in the MRR-Tri task of the Maximum Performance Tasks OR must demonstrate no childhood apraxia of speech (CAS-only) features in BOTH articulatory and rate/prosody domains of the ProCAD.
Must score <40% accurate based on word-level items from our /ɹ/ probe list.
Must score >=15% accuracy on /ɹ/ on 45 syllables following Dynamic Assessment.
Must express interest in changing their /ɹ/ production.
Must have oral structure and function that are appropriate for /ɹ/ production.
Must have access to broadband internet with videoconferencing capabilities
Exclusion Criteria:
Must have no known history of autism spectrum disorder, Down Syndrome, cerebral palsy, intellectual disability, permanent hearing loss, epilepsy/antiepileptic medication, or brain injury/neurosurgery/stroke.
Must not have diagnosis of attention deficit disorder, attention deficit hyperactivity disorder, Tourette's, or Obsessive-compulsive disorder.
Must have no orthodontic appliances that block the roof of the mouth (e.g., palate expanders).
Must not have current cleft palate, fluency disorder, or voice disorder.
Must not demonstrate childhood apraxia of speech (CAS-only) features in BOTH articulatory and rate/prosody domains of the ProCAD.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Jonathan Preston, PhD
Phone
315-443-1351
Email
jopresto@syr.edu
First Name & Middle Initial & Last Name or Official Title & Degree
Nina Benway, PhD
Email
nrbenway@syr.edu
Facility Information:
Facility Name
Syracuse University
City
Syracuse
State/Province
New York
ZIP/Postal Code
13244
Country
United States
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jonathan Preston, PhD
Phone
315-443-3143
Email
jopresto@syr.edu
First Name & Middle Initial & Last Name & Degree
Nicole Caballero, MS
Phone
315-443-1185
Email
nfcaball@syr.edu
12. IPD Sharing Statement
Links:
URL
https://speechproductionlab.syr.edu/research/
Description
Lab website with recruitment information
Learn more about this trial
AI-Assisted Treatment for Residual Speech Sound Disorders
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