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Financial Incentives and Recruitment to the APT Webstudy (FIND-AD)

Primary Purpose

Alzheimer Disease, Dementia, Preclinical Alzheimer's Disease

Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Financial Incentives
Message
Sponsored by
University of Southern California
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional health services research trial for Alzheimer Disease focused on measuring Alzheimer's, Prevention, Observational, Trial-Ready Cohort

Eligibility Criteria

50 Years - undefined (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria: To be eligible to participate in this study, an individual must meet all of the following criteria: Patients empaneled at Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers. Age 50 or older Literate in either English or Spanish Exclusion Criteria: Below age 50 Documentation of prior dementia diagnosis

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm 3

    Arm Type

    Active Comparator

    Experimental

    Experimental

    Arm Label

    Messaging Only

    Small Incentive

    Prize Incentive

    Arm Description

    16,000 participants will be randomized to Arm 1 where no monetary incentive is offered.

    16,000 participants will be randomized to Arm 2 where a small one-time monetary incentive is offered.

    16,000 participants will be randomized to Arm 3 where an opportunity based incentive (or a drawing with a prize) with a single winner will be offered.

    Outcomes

    Primary Outcome Measures

    Enrollment status into the APT Webstudy
    APT Webstudy enrollment rate based on completion of at least one of the two APT Webstudy cognitive assessments (Cognitive Function Instrument [CFI] and/or Cogstate Brief Battery).

    Secondary Outcome Measures

    Cost per enrollee
    Cost to acquire an enrollment
    Completion of cognitive assessments within the APT Webstudy
    Completion of both APT Webstudy cognitive assessments (Cognitive Function Instrument [CFI] and/or Cogstate Brief Battery).

    Full Information

    First Posted
    August 9, 2023
    Last Updated
    September 7, 2023
    Sponsor
    University of Southern California
    Collaborators
    American Heart Association, Schaeffer Center for Health Policy & Economics, Alzheimer's Therapeutic Research Institute
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    1. Study Identification

    Unique Protocol Identification Number
    NCT06033066
    Brief Title
    Financial Incentives and Recruitment to the APT Webstudy
    Acronym
    FIND-AD
    Official Title
    A Randomized Trial of Financial Incentives for the Recruitment of County Health System Patients to the Alzheimer Prevention Trials (APT) Webstudy
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    September 2023
    Overall Recruitment Status
    Not yet recruiting
    Study Start Date
    September 2023 (Anticipated)
    Primary Completion Date
    March 2026 (Anticipated)
    Study Completion Date
    March 2026 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    University of Southern California
    Collaborators
    American Heart Association, Schaeffer Center for Health Policy & Economics, Alzheimer's Therapeutic Research Institute

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No
    Data Monitoring Committee
    No

    5. Study Description

    Brief Summary
    This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpose of the current study is to test whether we can increase enrollment of diverse individuals into the registry. To do this, we will work with Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers in Contra Costa County, California, to test whether sending messages with and without financial incentives to patients who receive primary care with the health system can increase enrollment to the APT Webstudy. The investigators hypothesize that 1) a certain small financial incentive and an award opportunity based incentive (or a drawing with a prize) will increase enrollment rates of CCHS members into the APT Webstudy relative to the control group. The investigators further hypothesize that the award opportunity incentive will increase the enrollment rate of CCRMC patients into the APT Webstudy more than a certain financial incentive with the same expected value.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Alzheimer Disease, Dementia, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease
    Keywords
    Alzheimer's, Prevention, Observational, Trial-Ready Cohort

    7. Study Design

    Primary Purpose
    Health Services Research
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Masking
    None (Open Label)
    Allocation
    Randomized
    Enrollment
    48000 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    Messaging Only
    Arm Type
    Active Comparator
    Arm Description
    16,000 participants will be randomized to Arm 1 where no monetary incentive is offered.
    Arm Title
    Small Incentive
    Arm Type
    Experimental
    Arm Description
    16,000 participants will be randomized to Arm 2 where a small one-time monetary incentive is offered.
    Arm Title
    Prize Incentive
    Arm Type
    Experimental
    Arm Description
    16,000 participants will be randomized to Arm 3 where an opportunity based incentive (or a drawing with a prize) with a single winner will be offered.
    Intervention Type
    Behavioral
    Intervention Name(s)
    Financial Incentives
    Intervention Description
    Small financial incentive or prize incentive
    Intervention Type
    Behavioral
    Intervention Name(s)
    Message
    Intervention Description
    Message inviting participant to enroll
    Primary Outcome Measure Information:
    Title
    Enrollment status into the APT Webstudy
    Description
    APT Webstudy enrollment rate based on completion of at least one of the two APT Webstudy cognitive assessments (Cognitive Function Instrument [CFI] and/or Cogstate Brief Battery).
    Time Frame
    2-weeks
    Secondary Outcome Measure Information:
    Title
    Cost per enrollee
    Description
    Cost to acquire an enrollment
    Time Frame
    annual
    Title
    Completion of cognitive assessments within the APT Webstudy
    Description
    Completion of both APT Webstudy cognitive assessments (Cognitive Function Instrument [CFI] and/or Cogstate Brief Battery).
    Time Frame
    2-weeks

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    50 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: To be eligible to participate in this study, an individual must meet all of the following criteria: Patients empaneled at Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers. Age 50 or older Literate in either English or Spanish Exclusion Criteria: Below age 50 Documentation of prior dementia diagnosis

    12. IPD Sharing Statement

    Plan to Share IPD
    Yes
    IPD Sharing Plan Description
    The health system will not allow sharing of individual data on a public site. However, we will share data on request from investigators.
    IPD Sharing Time Frame
    Data will be made available within 6 months of publication.
    IPD Sharing Access Criteria
    Individual data shared upon request.
    Links:
    URL
    https://www.aptwebstudy.org/
    Description
    APT Webstudy

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