Ultra Crave: An Investigation of Ultra-Processed Food
Food Addiction
About this trial
This is an interventional basic science trial for Food Addiction focused on measuring Withdrawal, Food Addiction, Highly Processed Foods
Eligibility Criteria
Inclusion Criteria: 25 to 60 years of age English-speaking Must own an Android or iPhone Smartphone Live within a 1-hour radius of the laboratory endorsement of > 4 symptoms on the YFAS 2.0 completed during eligibility screener; at the time of consent, symptom count must remain above threshold for food addiction (this discrepany is based on a previously found tendency during pilot testing to overestimate food addiction symptoms at the time of screening) endorse daily intake of multiple UP foods likes chocolate milkshake (fMRI) willing to follow dietary instructions provided by team willing to come to lab 3 times Exclusion Criteria: participants with a self-reported BMI < 18.5 and > 40 current diagnoses of disorders that can impact reward, metabolic functioning, or the ability to complete the imaging protocol (e.g., seizures, Tourette's, cancer, Irritable bowel syndrome, Inflammatory bowel disease, Hypothyroidism, substance use disorder, ADHD) Type 1 or Type 2 diabetes, pre-diabetes, hypoclycemia history of food allergies or restrictive dietary requirements (e.g., vegan) medications that impact appetite or reward functioning (e.g., anti-psychotic medication, insulin) history of diagnosis of a severe mental illness (e.g., bipolar, schizophrenia, psychotic disorder) a diagnosis of a restrictive eating disorder (anorexia nervosa, bulimia nervosa, purging disorder) within the last 5 years more than a 20-pound weight fluctuation in the last three months prior weight loss surgery (e.g., bariatric surgery) current pregnancy, breast-feeding, trying to get pregnant, or within six months of having given birth high levels of caffeine (i.e., average daily intake over 600mg) intake use of tobacco, nicotine, cannabis products within the past month and/or unwillingness to abstain from these substances during the main portion of the study high-risk alcohol use (based on the AUDIT) high levels of picky eating fMRI contraindications (e.g., claustrophobia, metal implants) red/green color blindness frequent (i.e., weekly) night shift work or irregular shifts and for abnormal sleep patterns (i.e., wake up time after 11am) inability to complete a random report within 90 minutes THC Cannabis within the past week
Sites / Locations
- University of MichiganRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Low UP Food Diet
High UP Food Diet