Liquid Biopsy for the Diagnosis of Intestinal-type Adenocarcinoma of the Ethmoid (BLADE) (BLADE)
Ethmoid Sinus Tumor, Adenocarcinoma, Circulating Tumor Cell
About this trial
This is an interventional diagnostic trial for Ethmoid Sinus Tumor
Eligibility Criteria
Inclusion Criteria: Case group: diagnosis of adenocarcinoma of the ethmoid on biopsy or imaging recurence; age>/= 18 years; patient consent ; Age and gender-matched control group: consulting patient in otolaryngology head and neck surgery department without adenocarcinoma of the ethmoid; no personal history of cancer; no familial history of colorectal adenocarcinoma; Exposition control group: Professional exposition to wood dust, leaver or nickel for at least 12 months; consulting patient in otolaryngology head and neck surgery department without adenocarcinoma of the ethmoid; no personal history of cancer; no familial history of colorectal adenocarcinoma; Exclusion Criteria: patient presenting with another malignant tumor deprivation of liberty patient under guardianship Other cancer diagnosed or under treatment Recurrent patient previously included in the study Refusal to accept the monitoring described and/or to provide the information required for the study No affiliation or non-beneficiary of a Social Security system; Pregnant or breast-feeding women in accordance with article L1121-5 of the Public Health Code (CSP)
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Active Comparator
Cases: adenocarcinoma of the ethmoid Group1
Age-matched controls Group 2
Exposition-matched controls Group 3
Liquid biopsy at the inclusion (V0), d8-d10 (V1) and m2-m3 (V2) of postoperative follow-up.
Liquid biopsy at the inclusion (V0) only
Liquid biopsy at the inclusion (V0) only