Non-invasive Brain Stimulation and Injury Risk Biomechanics
Concussion, Mild
About this trial
This is an interventional prevention trial for Concussion, Mild focused on measuring concussion, repetitive transcranial magnetic stimulation, mild traumatic brain injury, biomechanics, reaction time, theta burst stimulation
Eligibility Criteria
Inclusion Criteria: All participants self-report to be physically active at least 90 minutes per week aged 18-35 years old self-report cleared for sports and physical activity Concussion history group - self-report experiencing a concussion with the National Institute of Health common data element form No concussion history group - self-report not experiencing a concussion with the National Institute of Health common data element form Exclusion Criteria: All Participants self-report attention deficit disorder and/or attention deficit hyperactivity disorder self-report uncorrected vision problems (not included color blindness) self-reported history of neurological disease self-reported history of seizures/syncope or family history of epilepsy self-reported history of frequent severe headaches or migraine. self-reported history of respiratory or heart disease. self-reported structural brain lesions (e.g., stroke) self-reported increased intracranial pressure, such as after infarctions or trauma. self-reported currently using antidepressants, neuroleptic medication, medication that lowers seizure threshold, or any other medication that would interfere with testing. self-reported currently experiencing a high fever (day of testing; >102.9 degrees) self-reported currently undergoing immunosuppressive therapy pregnancy metal anywhere in the head (except the mouth). any electronic implant, such as a cardiac pacemakers, cochlear implant, or deep brain stimulator. any implanted medication pump or intracardiac lines. self-report not being cleared for sport/physical activity by a medical practitioner (i.e., must be cleared by a medical practitioner to participate if the participant had previous traumatic musculoskeletal injury) students working directly in the PI's lab (concussion laboratory, biomechanics laboratory) NCAA athletes Concussion history group - ≥13 symptom severity on the Sport Concussion Assessment Tool (22 total symptoms are graded on a scale of 0-6. Any symptom with a score >0 [1-6], is summed to get symptom severity).
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Left Dorsolateral Prefrontal Cortex (experimental)
Vertex (control)
This is the experimental condition where participants will receive theta burst stimulation to the left dorsolateral prefrontal cortex.
This is the control condition where participants will receive theta burst stimulation to the vertex.