A Clinical Research Study Designed To Determine If Treatment of Hepatitis C With Milk Thistle is More Effective Than No Treatment In Patients Infected With Both HIV And Hepatitis C
HIV Infections, Hepatitis C
About this trial
This is an interventional treatment trial for HIV Infections focused on measuring HIV, Hepatitis C
Eligibility Criteria
Inclusion Criteria: Men and women 18 years old and older Blood tests that are positive for a certain type of Hepatitis C known as HIV + Blood tests for liver function that indicate that the liver is working - must be obtained within one month of study entry CD4 counts and HIV viral loads obtained within one month of study entry (CD4 count <100 - eligible if HIV Viral Load <25,000) (CD4 >100 - eligible with any HIV Viral Load) Exclusion Criteria: Women who are pregnant & breast-feeding & male partners of pregnant women Diagnosis of advanced liver disease Chronic liver disease other than Hepatitis C HIV related infection within two weeks of study entry Having had any organ transplant in the past including bone marrow History of mental illness including depression within three months of study entry and attempted suicide or hospitalization for the treatment of mental illness at any time in the past Chemotherapy treatment or treatment with steroids or other drugs that affect the immune system within six months of study entry Problems with alcohol of illegal drugs within one year of study entry. Patients on methadone will be allowed to enter the study.
Sites / Locations
- Mount Sinai School of Medicine
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Silymarin
Placebo
Silymarin
Placebo