A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses (TTIP-PRO)
Drug Overdose, Opioid-Related Disorders, Drug Addiction
About this trial
This is an interventional prevention trial for Drug Overdose focused on measuring Opioid Substitution Treatment, Telephone intervention, secondary prevention, naloxone
Eligibility Criteria
Inclusion Criteria:
- Report having been treated for an OOD within the past 6 months
- Age 18 years or older;
- Scores "high risk" for heroin and/or non-medical use of prescription opioids on the National Institute on Drug Abuse modified Alcohol, Smoking and Substance Involvement Screening Test (NIDA-modified ASSIST) (i.e., ≥ 27)
- Be able to understand the study, and having understood, provide written informed consent in English
- Access to a phone (for TTIP-PRO intervention and phone follow-up)
- Be willing to have their intervention audio recorded and rated if randomized to TTIP-PRO
- Have an opioid-positive baseline/screening urine drug screen.
Exclusion Criteria:
- In the judgment of the investigator, would not be expected to complete the study protocol (e.g., due to relocation from the clinic area, probable incarceration, etc.)
- Current engagement in addiction treatment
- Residence more than 40 miles from the location of follow-up visits
- Inability to provide sufficient contact information (must provide at least 2 reliable locators)
- Prior participation in the current study.
Sites / Locations
- University of Cincinnati Addiction Sciences Division
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
PTOEND
PTOEND+PI
PTOEND: Personally-tailored opioid overdose prevention education and naloxone distribution. Participants in this arm will be given a NARCAN (naloxone) nasal spray kit and personally-tailored information packet about opioid overdose and treatment.
PTOEND+PI: Personally-tailored opioid overdose prevention education and naloxone distribution, plus Peer Intervention. In addition to a NARCAN (naloxone) nasal spray kit and personally-tailored information packet about opioid overdose and treatment, participants randomized to this arm will also receive the experimental Peer Intervention.