An Optimized Programming of Healthy Children (APPROACH)
Pregnancy, Obesity, Gestational Age and Weight Conditions
About this trial
This is an interventional prevention trial for Pregnancy focused on measuring Gestational weight gain, Obese women, Fetal programming, Metabolic disorders, Development of obesity, Development og overweight, Complications during pregnancy and birth
Eligibility Criteria
Inclusion Criteria:
- Birth planed at Copenhagen University Hospital Herlev
- Pre-pregnancy BMI 28-45
- Age 18-42 years
- Speak and understand oral and written Danish
- Singleton pregnancy
Exclusion Criteria:
- Multiple pregnancy
- History of spontaneous abortions or gestational diabetes or preeclampsia or spontaneous preterm birth
- Dairy product intolerant or allergic
- > 10 kg weight change during the past year
- Abuse of alcohol or drugs (>14 units of alcohol per week)
- Critical or chronic disease: diabetes, kidney disease, medically treated heart diseases or arthritis, sarcoidosis, tuberculosis, cancer, liver disease, inflammatory gastrointestinal or lung disease, known active metabolic disease.
Sites / Locations
- University of Copenhagen, Faculty of Sceience, NEXS
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
High-protein/Low-GI Diet
Low-protein/High-GI Diet
High-protein (25-28 E%), especially marine- and dairy-protein (8-10 E%) and low-GI (GI<55) ad libitum Diet in accordance with the principles of palatability and sustainability of the New Nordic Diet.
Ad libitum diet based on the Danish National Guidelines (NNR) (protein 10-20 E%; no information on restricting glycaemic load (GI ~ 60)) and in accordance with the principles of palatability and sustainability of the New Nordic Diet.