Cerebellar rTMS Theta Burst for Dual-task Walking in Parkinson's Disease
Parkinson, Parkinson Disease, Gait Disorders, Neurologic
About this trial
This is an interventional treatment trial for Parkinson focused on measuring repetitive Transcranial Magnetic stimulation, rTMS, wearing sensors, wearables, step variability, gait variability, gait speed, dual-task, dual-task walking, turning
Eligibility Criteria
Inclusion Criteria:
- established Parkinson's disease
- ability to stand alone and walk without support
Exclusion Criteria:
- dementia or behavioral alterations
- contraindication to stimulation
Sites / Locations
- Parkinson's disease Rehabilitation Centre - FERB ONLUSRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Real Stimulation
Sham Stimulation
Cerebellar Repetitive theta burst stimulation will be performed using a 3 pulses at 50-Hz repeated at a rate of 5-Hz; 20 trains of 10 bursts given with 8-s intervals for a total of 600 pulses. Intensity of rTMS was set at the 80% of Amplitude of Motor Threshold (RMT) obtained in the left motor cortex for each subject.
The rTMS coil stimulation will be applied in the same position of the real stimulation. The Stimulation will be performed like in the real arm with the difference that the coil will be masked and thus will be inactive. The patient will hear the same sound of real stimulation, which will be only functionally inactive but will be completely performed (for the whole time of duration of stimulation)