Combined Transcranial Magnetic Stimulation and Therapy for mTBI Related Headaches
TBI (Traumatic Brain Injury), Headache, Depression
About this trial
This is an interventional treatment trial for TBI (Traumatic Brain Injury) focused on measuring rTMS, transcranial magnetic stimulation, therapy
Eligibility Criteria
Inclusion Criteria:
- Mild Traumatic Brain Injury (mTBI)
- Chronic headaches > 3 months after injury
- Aged 18-65
- No prior TMS treatment
- Persistent Headaches with an intensity > 30 / 100
- No history of daily headache prior to mTBI
Exclusion Criteria:
- Pregnant
- Pacemaker or any metal in body that would prevent MRI
- History of dementia or major psychiatric disease, such as bipolar disorder or schizophrenia
- Presence of any other chronic neuropathic pain states
- History of seizure
- Pending litigation
- Can't understand English
- History of chronic headache like migraine prior to mTBI
- Evidence in chart of exacerbation of depressive/anxiety symptoms, active substance dependence, suicidal intent or attempt within previous month
Sites / Locations
- VA San Diego Healthcare SystemRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Other
Other
Sham Comparator
Active rTMS with telehealth headache management therapy
Active rTMS with telehealth headache education control
Sham rTMS with telehealth headache management therapy
Sham rTMS with telehealth headache education control
Participants receive both active rTMS treatment at the left dorsolateral prefrontal cortex and therapy for headache management
Participants receive active rTMS treatment at the left dorsolateral prefrontal cortex and headache education
Participants receive sham rTMS treatment at the left dorsolateral prefrontal cortex and therapy for headache management
Participants receive sham rTMS treatment at the left dorsolateral prefrontal cortex and headache education