Comparison of Continuous Versus Intermittent Enteral Nutrition in Critically Ill Patients. (COINN)
Nutrition Disorders
About this trial
This is an interventional treatment trial for Nutrition Disorders focused on measuring Critical Care, Enteral Nutrition, Ventilator Associated Pneumonia, Gastric Residual Volume
Eligibility Criteria
Inclusion Criteria:
- age between 18 - 80 years
- indication of enteral nutrition with nasogastric or orogastric tube
- Nutrition Risk in the Critically Ill (NUTRIC) score ≥5
- Body mass index between 18 - 50
- mechanical ventilation expected for at least 72 hours
Exclusion Criteria:
- upper gastrointestinal tract surgery in previous medical history
- bowel obstruction
- bowel ischemia
- acute pancreatitis
- severe diarrhoea (>1l/24hours)
- gastrointestinal bleeding
- short bowel syndrome
- malabsorption syndrome in previous medical history
- ongoing enteral nutrition on admission to ICU
Sites / Locations
- University Hospital Brno and Masaryk University BrnoRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Intermittent
Continuous
enteral nutrition will be administered via enteral feeding pump as 30-60minutes lasting bolus 6 times per day volume of initial bolus will be 80ml. The volume of bolus will be increased gradually according to tolerance, till the estimated target rate will be reached
enteral nutrition will be administered via enteral feeding pump for at least 16 hours par day initial rate will be 25ml/hour. The rate will be increased gradually according to tolerance, till the estimated target rate will be reached