Comparison of Externally Versus Internally Cooled Tip Catheter Ablation in Paroxysmal Atrial Fibrillation (CATAFABL)
Atrial Fibrillation
About this trial
This is an interventional treatment trial for Atrial Fibrillation focused on measuring FA, Atrial fibrillation, Catheter, Ablation, RF
Eligibility Criteria
Inclusion Criteria:
- Adults (≥18 years old)
- Drug refractory paroxysmal AF with episods lasting <24hours
- Follow-up possible at one of the 2 institutions performing the study
- Oral agreement of the patient after reading the document of information
Exclusion Criteria:
- Pregnancy
- Psychiatric troubles not stabilized
- Contraindication to undergo AF ablation
- Previous attempt at AF ablation
- Cardioversion for AF
- No oral agreement of the patient for the study
Sites / Locations
- University Hospital
- Clinique Pasteur
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
1
2
The externally irrigated-tip catheter is an "open system" in which saline is continuously infused and empties into the blood pool. For the externally irrigated-tip catheter, RF energy delivery settings were: power ≤ 35 watts and temperature ≤ 43°C with a variable flow-rate to obtain a temperature around 40°C.
For the internally irrigated tip catheter (reference catheter), radiofrequency (RF) energy delivery settings will be: power ≤ 35 watts, temperature ≤ 47◦C and a fixed flow rate of 0.6 ml/s. The advantage of the Chili thermo-cooled tip system is that no saline solution leaves the catheter system and flows into the patient.