Continuous Glucose Monitoring for Hyperglycemia in Critically Ill Patients
Hyperglycemia, Hypoglycemia, Critical Illness
About this trial
This is an interventional treatment trial for Hyperglycemia
Eligibility Criteria
Inclusion Criteria:
- Patients age 18-89
- Past medical history of any diabetes mellitus OR patients with at least 1 measured BG of 180 being treated with insulin (subcutaneous or infusion)
- Enrollment will occur within 72 hours after being admitted to an ICU if history of diabetes
- Enrollment will occur within 72 hours after developing hyperglycemia in ICU if no diabetes
Exclusion Criteria:
- Pregnant patients
- Patients using CGMs in the outpatient setting
- Diagnosis of diabetic ketoacidosis (DKA)
- Diagnosis of hyperosmolar hyperglycemic state (HHS)
- Anticipated to require prone positioning while on insulin therapy
- Any contraindications to CGMs based on manufacturer labeling
- BG above maximum reading for CGM (e.g. greater than 400 mg/dL)
- Receiving medication that could interfere with CGM readings (based on manufacturer specifications)
- Receiving any dose of hydroxyurea as this could falsely elevate the sensor readings (if applicable for specific CGM)
- Receiving greater than 1,000mg acetaminophen every 6 hours in any form as this could falsely elevate the sensor readings (if applicable for specific CGM)
Sites / Locations
- North Florida/South Georgia Veterans Health SystemRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Continuous Glucose Monitoring
Point of Care Glucose Monitoring
Study subjects in this arm will receive glycemic management based on continuous glucose monitoring with CGM device. CGM readings will be available to patients, nurses, and the treating team. All treatment decisions for this group will be based on CGM readings, confirmatory POC readings (as necessary), and venipuncture.
Study subjects in this arm will receive glycemic management based on point of care blood glucose readings. CGM will be placed in blinded mode and used for study comparison only. Patients, nurses, and other treatment team will be blinded to the CGM readings. All treatment decisions for this group will be based on POC readings and venipuncture