Development of a Mind Body Program for Obese Knee Osteoarthritis Patients With Comorbid Depression (GetHealthy-OA)
Knee Osteoarthritis, Obesity, Depression
About this trial
This is an interventional treatment trial for Knee Osteoarthritis
Eligibility Criteria
Inclusion Criteria:
- Obese patients (BMI > 30 kg/m2)
- Idiopathic knee OA per the American College of Rheumatology classification with mild to moderate radiographic changes (Kellgren/Lawrence grade 2 or 3)
- Current elevated depressive symptoms (PHQ-9 > 9)
- Age 45 or older
- Free of concurrent psychotropics for < 2 weeks prior to initiation of treatment or on stable doses for > 6 weeks
- Access to a computer/smart phone with internet access
- Willingness to comply with the study protocol and assessments
- Cleared by a medical doctor to participate
Exclusion Criteria:
- Any disorder requiring the use of systemic corticosteroids
- Rheumatoid arthritis
- History of cancer within 5 years of screening
- Unable to walk/wheelchair-bound
- Prior surgical fixation of a femur or tibia fracture
- Taking high doses of opioid pain medication (50 milligrams of morphine equivalent)
- Diagnosis of a medical illness expected to worsen in the next 6 months (e.g., malignancy)
- Active suicidal ideation or past-year psychiatric hospitalization
- Non-English speaking
- Current severe depression symptoms (PHQ-9 > 19)
- Lifetime history of schizophrenia, bipolar disorder, or other psychotic disorder
- Current substance abuse or dependence
- Substance use disorder within the past 6 months
- Practice of yoga/meditation, or other mind body techniques that elicit the relaxation response, once per week for 45 min or more within the last 3 months
- Engagement in regular moderate or vigorous physical exercise for >30 min daily
Sites / Locations
- UK Healthcare at Turfland
- UK HealthCare Joint Reconstruction and Replacement
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
GetHealthy-OA
Health Enhancement Program
The GetHealthy-OA is an 6-week group mind body program with efficacy in improving depression, physical function and aiding in weight loss, that has been adapted for the unique needs of patients with knee osteoarthritis, depression and obesity. The GetHealthy-OA will be delivered by secure telehealth.
The Health Enhancement Program is a chronic pain-specific program adapted for the specific needs of patients with knee osteoarthritis. It is an 6-week group mind body program that will be delivered via secure telehealth. To control for in between session practice, participants will receive an mp3 recording and informational handout to complete after each session.