Back to resultsEffect of Exercise on Vitamin d in Obese
Primary Purpose
Obesity, Vitamin D Deficiency
Status
Completed
Phase
Not Applicable
Locations
Saudi Arabia
Study Type
Interventional
Intervention
Endurance exercise
Resistance exersises.
Sponsored by
About this trial
This is an interventional treatment trial for Obesity
Eligibility Criteria
Inclusion Criteria:
- Body mass index percentile equal to or greater than the 95th percentile
- All did not receive strength or balance training or involvement in competitive sports emphasizing muscular strength.
- All participants had balance deficiency and mobile flat foot.
- 25(OH) D was ranged from 10-20ng/ml
Exclusion Criteria:
- Injury to the lower limb required medical care.
- Deformity of or surgery in the lower limb.
- Visual impairment, or neuromuscular disorders.
- Engagement in obesity treatment programs, three months prior to the study.
- Epileptic fits
- Thyroid medications
- Autoimmune disease
- Take calcium or vitamin d3 supplements, medications for osteoporosis
Sites / Locations
- College of applied medical sciences
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Experimental
Arm Label
endurance exercise
resistance exersise plus endurance exersise
Arm Description
This group received endurance exercises only.
This group received resistance exercises followed by endurance exercises.
Outcomes
Primary Outcome Measures
Free fatty acids
Plasma level of the free fatty acids immediatlly after the exercise.
Glycerol
Plasma level of glycerol immediatlly after the exercise.
Vitamin D
Plasma level of 25 (OH) D immediatlly after the exercise.
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT05066490
Brief Title
Effect of Exercise on Vitamin d in Obese
Official Title
Effect of Exercise-induced Lipolysis on Vitamin D Status in Obese Children
Study Type
Interventional
2. Study Status
Record Verification Date
December 2021
Overall Recruitment Status
Completed
Study Start Date
October 6, 2020 (Actual)
Primary Completion Date
February 15, 2021 (Actual)
Study Completion Date
March 25, 2021 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Taif University
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
5. Study Description
Brief Summary
The aim of the current study was to investigate the effect of exercise-induced lipolysis on vitamin D status in obese children. Two types of exercises that have different effects on lipolysis were used. Lipolysis was assessed via monitoring the level of plasma level of the free fatty acids and glycerol. Vitamin D was assessed through 25 (OH)D plasma levels.
Detailed Description
vitamin D status was monitored through 25 (OH)D levels, and the lipolysis status via the plasma level of the free fatty acids and glycerol immediately after the exercise. All subjects who participated in the study were under supervision for controlling the fat contents and vitamin D in their food for one week prior to the exercise. the subjects fasted eight hours before the exercise. All the exercises were performed between 9 am and 11 am.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity, Vitamin D Deficiency
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Model Description
40 obese children who suffered from vitamin d deficiency were randomly assigned into three groups. group I (15 children) received endurance exercises and group II (15 children) received endurance exercises preceded by resistance exercises which have a stronger lipolytic effect. group III (10 children) acted as a control group.
Masking
ParticipantCare ProviderOutcomes Assessor
Allocation
Randomized
Enrollment
30 (Actual)
8. Arms, Groups, and Interventions
Arm Title
endurance exercise
Arm Type
Experimental
Arm Description
This group received endurance exercises only.
Arm Title
resistance exersise plus endurance exersise
Arm Type
Experimental
Arm Description
This group received resistance exercises followed by endurance exercises.
Intervention Type
Other
Intervention Name(s)
Endurance exercise
Intervention Description
Treadmill training at moderate intensity.
Intervention Type
Other
Intervention Name(s)
Resistance exersises.
Intervention Description
Resistance exercises using the 10 repetition maximum.
Primary Outcome Measure Information:
Title
Free fatty acids
Description
Plasma level of the free fatty acids immediatlly after the exercise.
Time Frame
After 60 min of training
Title
Glycerol
Description
Plasma level of glycerol immediatlly after the exercise.
Time Frame
After 60 min of training
Title
Vitamin D
Description
Plasma level of 25 (OH) D immediatlly after the exercise.
Time Frame
After 60 min of training
10. Eligibility
Sex
Male
Minimum Age & Unit of Time
7 Years
Maximum Age & Unit of Time
10 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Body mass index percentile equal to or greater than the 95th percentile
All did not receive strength or balance training or involvement in competitive sports emphasizing muscular strength.
All participants had balance deficiency and mobile flat foot.
25(OH) D was ranged from 10-20ng/ml
Exclusion Criteria:
Injury to the lower limb required medical care.
Deformity of or surgery in the lower limb.
Visual impairment, or neuromuscular disorders.
Engagement in obesity treatment programs, three months prior to the study.
Epileptic fits
Thyroid medications
Autoimmune disease
Take calcium or vitamin d3 supplements, medications for osteoporosis
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Hatem H Allam, Doctoral
Organizational Affiliation
Assisstant professor
Official's Role
Study Director
Facility Information:
Facility Name
College of applied medical sciences
City
Taif
State/Province
Mecca
ZIP/Postal Code
2425
Country
Saudi Arabia
12. IPD Sharing Statement
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Effect of Exercise on Vitamin d in Obese
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