Effect of Low-Level Laser on Pain and Healing of Donor Site Following Free Gingival Graft

The Effect of Low-Level Laser Therapy on Patient's Pain and Healing of Palatal Donor Site Following Free Gingival Graft: A Randomized Controlled Clinical Trial

The aim of this randomized split-mouth design clinical trial is to clinically evaluate the effectiveness of diode laser in the healing of donor site of palate in free gingival graft.

Free gingival graft is the most predictable and successful method for increasing the width of keratinized tissue around teeth/dental implants and vestibular deepening. However, patient discomfort during the healing time is a major disadvantage of this procedure. Several methods have been introduced to accelerate the healing time and reduction of patient's pain during first days after surgery. Low-level lasers have shown promising results in biostimulation of cell growth and differentiation in cultures. However, there are lack of well designed double blind placebo controlled randomized controlled clinical studies evaluating the effects of Low-level laser therapy in acceleration of wound healing and pain relief of patients undergoing free gingival grafts.

Low-level laser (Diode, 66o nanometer, power:200 milli Watt (mW), Continuous wave, time of irradiation:32 seconds)is irradiated in donor site

Low-level laser therapy with the following parameters: Wavelength:660 nanometer, power: 200 mW, continuous mode, tme of irradiation: 32 seconds

Laser device is turned-off. All parameters are like experimental group, however the laser in turned-off.

3% hydrogen peroxide (H2O2) was applied to the wound by a sterile gause to see the bubbling Complete epithelialization: bubble was not seen Partial epithelialization: bubbles were seen in lesser than half of donor site No epithelialization: bubble were seen in more than half of donor site

3% hydrogen peroxide (H2O2) was applied to the wound by a sterile gause to see the bubbling Complete epithelialization: bubble was not seen Partial epithelialization: bubbles were seen in lesser than half of donor site No epithelialization: bubble were seen in more than half of donor site

3% hydrogen peroxide (H2O2) was applied to the wound by a sterile gause to see the bubbling Complete epithelialization: bubble was not seen Partial epithelialization: bubbles were seen in lesser than half of donor site No epithelialization: bubble were seen in more than half of donor site

Photographs were taken from donor and recipient sites. Three expert blinded periodontist photographs photographs based on shade,morphology and texture at two sessions by 48 hours interval.

Photographs were taken from donor and recipient sites. Three expert blinded periodontist photographs photographs based on shade,morphology and texture at two sessions by 48 hours interval.

Photographs were taken from donor and recipient sites. Three expert blinded periodontist photographs photographs based on shade,morphology and texture at two sessions by 48 hours interval.

Photographs were taken from donor and recipient sites. Three expert blinded periodontist photographs photographs based on shade,morphology and texture at two sessions by 48 hours interval.

Photographs were taken from donor and recipient sites. Three expert blinded periodontist photographs photographs based on shade,morphology and texture at two sessions by 48 hours interval.

Inclusion Criteria: lack of keratinized tissue around teeth (bilateral) Exclusion Criteria: patients with systemic diseases non-cooperative patients smokers poor oral hygiene root surface restorations or active caries