Effectiveness of Antidepressant Treatment for Depression in People With Parkinson's Disease
Depressive Disorder, Parkinson Disease
About this trial
This is an interventional treatment trial for Depressive Disorder focused on measuring Depression, Parkinson's Disease, Atomoxetine
Eligibility Criteria
Inclusion Criteria: Diagnosis of idiopathic Parkinson's disease IDS score greater than 21 Mini-Mental State Examination (MMSE) score greater than 15 Exclusion Criteria: Recent deep brain stimulation Currently participating in an antidepressant trial at a less than adequate dose and duration Severe depression or depression with suicide ideation History of liver toxicity Unstable medical disease or comorbid psychiatric disease
Sites / Locations
- Philadelphia Veterans Affairs Medical Center
- University of Pennsylvania
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Atomoxetine
Placebo
Participants will receive 40-80mgs of atomoxetine orally once daily.
Participants will receive placebo treatment once daily; the pill (taken orally) will resemble the atomoxetine pill but will not contain an active drug.