Back to resultsEffects of Exercise on Markers of Inflammation in Skeletal Muscle in Elderly Hip Fracture Patients
Primary Purpose
Hip Fractures, Muscular Atrophy
Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Exercise
Sponsored by
About this trial
This is an interventional treatment trial for Hip Fractures focused on measuring sarcopenia
Eligibility Criteria
Inclusion Criteria: Enrollment in HSC protocol #97-0695 "Rehabilitation Intensification Post Hip Fracture" Community-dwelling Hip fracture within 16 weeks of the screening assessment for protocol 97-0695 Persistent mobility and/or ADL impairments, but independent in ambulation Modified Physical Performance Test (PPT) score between 12 and 28
Sites / Locations
- Washington University
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
NCT ID
NCT00006194
First Posted
September 7, 2000
Last Updated
June 23, 2005
Sponsor
National Center for Research Resources (NCRR)
1. Study Identification
Unique Protocol Identification Number
NCT00006194
Brief Title
Effects of Exercise on Markers of Inflammation in Skeletal Muscle in Elderly Hip Fracture Patients
Study Type
Interventional
2. Study Status
Record Verification Date
December 2003
Overall Recruitment Status
Completed
Study Start Date
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Primary Completion Date
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Study Completion Date
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3. Sponsor/Collaborators
Name of the Sponsor
National Center for Research Resources (NCRR)
4. Oversight
5. Study Description
Brief Summary
Decreased skeletal muscle mass is a prevalent condition among the elderly, and an important cause of disability and functional decline. The declines in muscle mass associated with aging may be related to alterations in specific kinds of growth factors in the muscle. Elderly hip fracture patients often have significant decreases in muscle mass. The purpose of this study is to investigate whether an exercise program can induce changes in muscle growth factors that are associated with increases in muscle mass and strength in elderly hip fracture patients.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hip Fractures, Muscular Atrophy
Keywords
sarcopenia
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Allocation
Randomized
8. Arms, Groups, and Interventions
Intervention Type
Behavioral
Intervention Name(s)
Exercise
10. Eligibility
Sex
All
Minimum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Enrollment in HSC protocol #97-0695 "Rehabilitation Intensification Post Hip Fracture"
Community-dwelling
Hip fracture within 16 weeks of the screening assessment for protocol 97-0695
Persistent mobility and/or ADL impairments, but independent in ambulation
Modified Physical Performance Test (PPT) score between 12 and 28
Facility Information:
Facility Name
Washington University
City
St. Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
36070134
Citation
Fairhall NJ, Dyer SM, Mak JC, Diong J, Kwok WS, Sherrington C. Interventions for improving mobility after hip fracture surgery in adults. Cochrane Database Syst Rev. 2022 Sep 7;9(9):CD001704. doi: 10.1002/14651858.CD001704.pub5.
Results Reference
derived
Learn more about this trial
Effects of Exercise on Markers of Inflammation in Skeletal Muscle in Elderly Hip Fracture Patients
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