Effects of Rhythmic Auditory Cueing on Stepping in Place in Patients With Parkinson's Disease
Parkinson Disease
About this trial
This is an interventional treatment trial for Parkinson Disease focused on measuring Parkinson's disease, Auditory cues, step in place, transcranial magnetic stimulation, cortical excitability
Eligibility Criteria
[Patients with Parkinson's disease]
Inclusion Criteria:
- Diagnosed with idiopathic Parkinson's disease
- No hearing impairment
- Able to walk independently for at least 10m
- Able to follow command (MMSE >=24)
[Healthy subjects]
- No hearing impairment
- Able to walk independently for at least 10m
- Able to follow command (MMSE >=24)
Exclusion Criteria:
- With other neurological diseases or psychological diseases
- Dementia
- Family history of epilepsy
- History of head trauma, surgery, or metal implants
- Having pacemaker or other electrical stimulators
- History of syncopes or frequent migraines
Sites / Locations
- Department of physical therapy, National Taiwan University
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Freezer
Non-freezer
All the subjects received 2 experiments. 2 experiments contain 20 mins stepping-in-place exercise and pre-/post assessments. The difference between 2 experiments is the application of auditory cues. One of the 2 experiment includes stepping-in-place exercise with auditory cues from the metronome (Stepping-in-place exercise with external auditory cues), in the other experiment we ask the subjects to follow their internal rhythm without external auditory cues (Stepping-in-place exercise without external auditory cues). Transcranial magnetic stimulation (TMS) is applied before and after the stepping-in-place exercise.
All the subjects received 2 experiments. 2 experiments contain 20 mins stepping-in-place exercise and pre-/post assessments. The difference between 2 experiments is the application of auditory cues. One of the 2 experiment includes stepping-in-place exercise with auditory cues from the metronome (Stepping-in-place exercise with external auditory cues), in the other experiment we ask the subjects to follow their internal rhythm without external auditory cues (Stepping-in-place exercise without external auditory cues). Transcranial magnetic stimulation (TMS) is applied before and after the stepping-in-place exercise.