Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients
Primary Purpose
Headache, Epilepsy, Dizziness
Status
Unknown status
Phase
Phase 4
Locations
Germany
Study Type
Interventional
Intervention
Contrast agent
Sponsored by
About this trial
This is an interventional diagnostic trial for Headache focused on measuring magnetic imaging, angiography, contrast agent, signal/noise ratio, contrast/noise ratio, vessel
Eligibility Criteria
Inclusion Criteria: Headache Epilepsia Dizziness Exclusion Criteria: Pregnancy Metal implants (e.g. pacemaker) Contraindication for contrast agent Multiple allergies
Sites / Locations
- University of Muenster, Dept. of Clinical RadiologyRecruiting
Outcomes
Primary Outcome Measures
intensity of vessels, muscle, air
Secondary Outcome Measures
signal/noise ratio
contrast/nose ratio
Full Information
NCT ID
NCT00132223
First Posted
August 18, 2005
Last Updated
April 11, 2006
Sponsor
University Hospital Muenster
1. Study Identification
Unique Protocol Identification Number
NCT00132223
Brief Title
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients
Official Title
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients With Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging
Study Type
Interventional
2. Study Status
Record Verification Date
April 2006
Overall Recruitment Status
Unknown status
Study Start Date
April 2005 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
December 2005 (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
University Hospital Muenster
4. Oversight
5. Study Description
Brief Summary
Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.
Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients.
All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s.
The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Headache, Epilepsy, Dizziness
Keywords
magnetic imaging, angiography, contrast agent, signal/noise ratio, contrast/noise ratio, vessel
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Phase 4
Interventional Study Model
Single Group Assignment
Masking
Single
Allocation
Non-Randomized
Enrollment
10 (false)
8. Arms, Groups, and Interventions
Intervention Type
Drug
Intervention Name(s)
Contrast agent
Primary Outcome Measure Information:
Title
intensity of vessels, muscle, air
Secondary Outcome Measure Information:
Title
signal/noise ratio
Title
contrast/nose ratio
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
60 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Headache
Epilepsia
Dizziness
Exclusion Criteria:
Pregnancy
Metal implants (e.g. pacemaker)
Contraindication for contrast agent
Multiple allergies
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Boris Buerke, MD
Phone
00492518345123
Email
buerkeb@uni-muenster.de
First Name & Middle Initial & Last Name or Official Title & Degree
Bernd Tombach, MD
Phone
00492518345123
Email
tombach@uni-muenster.de
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Bernd Tombach, MD
Organizational Affiliation
University of Muenster, Dept. of Clinical Radiology
Official's Role
Study Chair
Facility Information:
Facility Name
University of Muenster, Dept. of Clinical Radiology
City
Muenster
ZIP/Postal Code
48129
Country
Germany
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Boris Buerke, MD
Phone
00492518345123
Email
buerkeb@uni-muenster.de
First Name & Middle Initial & Last Name & Degree
Bernd Tombach
Phone
00492518345123
Email
tombach@uni-muenster.de
First Name & Middle Initial & Last Name & Degree
Bernd Tombach, MD
First Name & Middle Initial & Last Name & Degree
Boris Buerke, MD
12. IPD Sharing Statement
Learn more about this trial
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients
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