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Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

Primary Purpose

Headache, Epilepsy, Dizziness

Status
Unknown status
Phase
Phase 4
Locations
Germany
Study Type
Interventional
Intervention
Contrast agent
Sponsored by
University Hospital Muenster
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional diagnostic trial for Headache focused on measuring magnetic imaging, angiography, contrast agent, signal/noise ratio, contrast/noise ratio, vessel

Eligibility Criteria

18 Years - 60 Years (Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Headache Epilepsia Dizziness Exclusion Criteria: Pregnancy Metal implants (e.g. pacemaker) Contraindication for contrast agent Multiple allergies

Sites / Locations

  • University of Muenster, Dept. of Clinical RadiologyRecruiting

Outcomes

Primary Outcome Measures

intensity of vessels, muscle, air

Secondary Outcome Measures

signal/noise ratio
contrast/nose ratio

Full Information

First Posted
August 18, 2005
Last Updated
April 11, 2006
Sponsor
University Hospital Muenster
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1. Study Identification

Unique Protocol Identification Number
NCT00132223
Brief Title
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients
Official Title
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients With Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging
Study Type
Interventional

2. Study Status

Record Verification Date
April 2006
Overall Recruitment Status
Unknown status
Study Start Date
April 2005 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
December 2005 (undefined)

3. Sponsor/Collaborators

Name of the Sponsor
University Hospital Muenster

4. Oversight

5. Study Description

Brief Summary
Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents. Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients. All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s. The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Headache, Epilepsy, Dizziness
Keywords
magnetic imaging, angiography, contrast agent, signal/noise ratio, contrast/noise ratio, vessel

7. Study Design

Primary Purpose
Diagnostic
Study Phase
Phase 4
Interventional Study Model
Single Group Assignment
Masking
Single
Allocation
Non-Randomized
Enrollment
10 (false)

8. Arms, Groups, and Interventions

Intervention Type
Drug
Intervention Name(s)
Contrast agent
Primary Outcome Measure Information:
Title
intensity of vessels, muscle, air
Secondary Outcome Measure Information:
Title
signal/noise ratio
Title
contrast/nose ratio

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
60 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Headache Epilepsia Dizziness Exclusion Criteria: Pregnancy Metal implants (e.g. pacemaker) Contraindication for contrast agent Multiple allergies
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Boris Buerke, MD
Phone
00492518345123
Email
buerkeb@uni-muenster.de
First Name & Middle Initial & Last Name or Official Title & Degree
Bernd Tombach, MD
Phone
00492518345123
Email
tombach@uni-muenster.de
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Bernd Tombach, MD
Organizational Affiliation
University of Muenster, Dept. of Clinical Radiology
Official's Role
Study Chair
Facility Information:
Facility Name
University of Muenster, Dept. of Clinical Radiology
City
Muenster
ZIP/Postal Code
48129
Country
Germany
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Boris Buerke, MD
Phone
00492518345123
Email
buerkeb@uni-muenster.de
First Name & Middle Initial & Last Name & Degree
Bernd Tombach
Phone
00492518345123
Email
tombach@uni-muenster.de
First Name & Middle Initial & Last Name & Degree
Bernd Tombach, MD
First Name & Middle Initial & Last Name & Degree
Boris Buerke, MD

12. IPD Sharing Statement

Learn more about this trial

Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

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