Enteroendocrine Hormonal Response After the Ingestion of Cola Beverages With Sucrose and Non-nutritive Sweeteners
Obesity, Diabetes Mellitus, Type 2, Metabolic Syndrome
About this trial
This is an interventional prevention trial for Obesity
Eligibility Criteria
Inclusion Criteria: Voluntary participation expressed through the signing of informed consent Exclusion Criteria: Pregnancy (date of last menstruation >28 days) History of diabetes mellitus or glucose intolerance, endocrinopathies, or pancreatic diseases Treatment with medications or supplements that modify glucose and insulin (eg antihypertensives, corticosteroids, hypoglycemic agents, hormonal agents, etc.) Gastrointestinal diseases or conditions that alter gastric emptying and intestinal transit Hypersensitivity to the compounds that will be used in the study
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Placebo Comparator
Experimental
Experimental
Active Comparator
Carbonated water
Cola beverage with aspartame and acesulfame K
Cola beverage with sucrose and stevia
Cola beverage with sucrose
355ml of an orally ingested carbonated water
355ml of an orally ingested carbonated cola drink, sweetened with 142mg of aspartame and acesulfame k, combined (soft drink in its commercial presentation)
355ml of an orally ingested carbonated cola drink, sweetened with 16g of sucrose and 15.62mg of stevia (soft drink in its commercial presentation)
355ml of an orally ingested carbonated cola drink, sweetened with 37g of sucrose