Back to resultsLower Extremity Muscle and Function in the Elderly: Study 2
Primary Purpose
Mobility Limitation
Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
High velocity low force Power Training
Low velocity high force Power Training
Sponsored by
About this trial
This is an interventional treatment trial for Mobility Limitation focused on measuring Resistance Exercise, Physical Activity, Mobility disability, Physical function, Muscle Strength, Older Adults, Mobility-Limited, Peak power and strength
Eligibility Criteria
Inclusion Criteria:
- Male and Female 70-85 yrs
- Community dwelling
- Short Performance Battery Score >9
- BMI range 19-32 kg/m2
- Willingness to be randomized and come the laboratory for 20 weeks.
Exclusion Criteria:
- Acute or Terminal Illness
- MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
- Upper or Lower extremity fracture in previous 6 months
- Uncontrolled hypertension (150/90mmHg)
- Neuromuscular diseases and drugs that affect neuromuscular function
- Hormone replacement therapy
- Participation in any regular endurance or resistance training exercise during previous 3 months
Sites / Locations
- Jean Mayer USDA Human Nutrition Research Center on Aging
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Experimental
Arm Label
High velocity low force Power Training
Low velocity high force Power Training
Arm Description
Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
Outcomes
Primary Outcome Measures
Leg Extensor Muscle Power
Leg extensor muscle power measured on pneumatic strength testing equipment at a external force consistent with 70% of the participant maximum leg extensor strength.
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT01614392
Brief Title
Lower Extremity Muscle and Function in the Elderly: Study 2
Official Title
Lower Extremity Muscle and Function in the Elderly: Study 2
Study Type
Interventional
2. Study Status
Record Verification Date
December 2018
Overall Recruitment Status
Completed
Study Start Date
September 2009 (undefined)
Primary Completion Date
October 2011 (Actual)
Study Completion Date
October 2011 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Tufts University
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Mobility Limitation
Keywords
Resistance Exercise, Physical Activity, Mobility disability, Physical function, Muscle Strength, Older Adults, Mobility-Limited, Peak power and strength
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Investigator
Allocation
Randomized
Enrollment
52 (Actual)
8. Arms, Groups, and Interventions
Arm Title
High velocity low force Power Training
Arm Type
Experimental
Arm Description
Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
Arm Title
Low velocity high force Power Training
Arm Type
Experimental
Arm Description
Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
Intervention Type
Behavioral
Intervention Name(s)
High velocity low force Power Training
Intervention Description
Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
Intervention Type
Behavioral
Intervention Name(s)
Low velocity high force Power Training
Intervention Description
Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
Primary Outcome Measure Information:
Title
Leg Extensor Muscle Power
Description
Leg extensor muscle power measured on pneumatic strength testing equipment at a external force consistent with 70% of the participant maximum leg extensor strength.
Time Frame
Change from baseline to Week 16
10. Eligibility
Sex
All
Minimum Age & Unit of Time
70 Years
Maximum Age & Unit of Time
85 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Male and Female 70-85 yrs
Community dwelling
Short Performance Battery Score >9
BMI range 19-32 kg/m2
Willingness to be randomized and come the laboratory for 20 weeks.
Exclusion Criteria:
Acute or Terminal Illness
MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
Upper or Lower extremity fracture in previous 6 months
Uncontrolled hypertension (150/90mmHg)
Neuromuscular diseases and drugs that affect neuromuscular function
Hormone replacement therapy
Participation in any regular endurance or resistance training exercise during previous 3 months
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Roger A Fieilding, Ph D.
Organizational Affiliation
Jean Mayer USDA Human Nutrition Research Center on Aging
Official's Role
Principal Investigator
Facility Information:
Facility Name
Jean Mayer USDA Human Nutrition Research Center on Aging
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02111
Country
United States
12. IPD Sharing Statement
Learn more about this trial
Lower Extremity Muscle and Function in the Elderly: Study 2
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