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Rhythmic Entrainment in Bilingual Speakers With Dysarthria

Primary Purpose

Parkinson Disease, Ataxia

Status
Terminated
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Auditory
Gestures
Sponsored by
Herbert H. Lehman College, City University of New York
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Parkinson Disease focused on measuring speech rhythm, speech therapy

Eligibility Criteria

21 Years - undefined (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • diagnosis of idiopathic Parkinson's disease (4) or dysarthria secondary to ataxia (4) or healthy (4)
  • monolingual speaker of American English (6) or native speaker of Spanish who speaks English with a Spanish accent (6)
  • age 21 or older

Exclusion Criteria:

  • Cognitive impairment that prevents participation in the therapy
  • Fluent speakers of languages other than English or Spanish
  • younger than 21 years

Sites / Locations

  • Lehman College

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Experimental

Arm Label

Gestures

Auditory

Arm Description

Use of hand gestures to improve speech rhythm and speech production

Use of auditory cues to improve speech rhythm and speech production

Outcomes

Primary Outcome Measures

Intelligibility
Intelligibility = the accuracy with which a listener understands a speaker. It will be measured by having the subjects undergoing the therapy ("the talkers") read 28 phrases using accompanying gesture or auditory cues and listeners will transcribe the sentences. The number of words accurately transcribed / the number of words in the phrase = intelligibility score for each phrase per listener

Secondary Outcome Measures

Ease of understanding
Ease of understanding = the ease with which listeners understand the speakers. It will be measured by having the subjects undergoing the therapy ("the talkers") read 28 phrases using accompanying gesture or auditory cues and listeners will rate how easy it is to understand the talkers using a 0 to 9 visual analog scale with 0 = very easy and 9= very hard, for each phrase per listener
Speech naturalness
Speech naturalness = the degree to which the listeners consider the speakers to have natural or unnatural speech. It will be measured by having the subjects undergoing the therapy ("the talkers") read 28 phrases using accompanying gesture or auditory cues and listeners will rate how natural-sounding the talker sounds by using a 0 to 9 visual analog scale with 0 = very natural and 9 = very unnatural, for each phrase per listener

Full Information

First Posted
August 21, 2018
Last Updated
February 22, 2019
Sponsor
Herbert H. Lehman College, City University of New York
Collaborators
University of Utah
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1. Study Identification

Unique Protocol Identification Number
NCT03645265
Brief Title
Rhythmic Entrainment in Bilingual Speakers With Dysarthria
Official Title
Rhythmic Entrainment in Bilingual Speakers With Dysarthria
Study Type
Interventional

2. Study Status

Record Verification Date
February 2019
Overall Recruitment Status
Terminated
Why Stopped
Results showing no effect
Study Start Date
September 1, 2018 (Actual)
Primary Completion Date
February 20, 2019 (Actual)
Study Completion Date
February 20, 2019 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Herbert H. Lehman College, City University of New York
Collaborators
University of Utah

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
The objectives of this study are to determine i) the effect of rhythmic entrainment of speech with hand gestures and auditory rhythmic cues on intelligibility and speech naturalness in Spanish-accented speakers of English in two pathology groups: ataxic dysarthria and hypokinetic dysarthria secondary to idiopathic Parkinson's disease; and ii) the extent to which speech rate and effort are control parameters of entrainment. These objectives will be achieved with the following specific aims: Specific Aim 1: Determine the effect of three rates of hand gestures and auditory rhythmic cues and the degree to which learning and carry-over occur. Specific Aim 2: Determine the effect of increased speech effort, operationalized as clear speech, and the interaction effect of clear speech with hand gestures and auditory rhythmic cues. Specific Aim 3: Investigate the perception of speech rhythm and its relationship to entrainment.
Detailed Description
The objectives of this study are to determine i) the effect of rhythmic entrainment of speech with hand gestures and auditory rhythmic cues on intelligibility and speech naturalness in Spanish-accented speakers of English in two pathology groups: ataxic dysarthria and hypokinetic dysarthria secondary to idiopathic Parkinson's disease; and ii) the extent to which speech rate and effort are control parameters of entrainment. These objectives will be achieved with the following specific aims: Specific Aim 1: Determine the effect of three rates of hand gestures and auditory rhythmic cues and the degree to which learning and carry-over occur. Specific Aim 2: Determine the effect of increased speech effort, operationalized as clear speech, and the interaction effect of clear speech with hand gestures and auditory rhythmic cues. Specific Aim 3: Investigate the perception of speech rhythm and its relationship to entrainment. The protocol calls for 12 talkers to participate in a single case experimental design: 6 Spanish-accented speakers of English and 6 native English speakers, and each language group consisting of 2 healthy controls, 2 adults diagnosed with ataxic dysarthria and 2 adults diagnosed with hypokinetic dysarthria secondary to idiopathic Parkinson's disease. Sixty monolingual healthy adult listeners will rate intelligibility, accentedness, and ease of understanding.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Parkinson Disease, Ataxia
Keywords
speech rhythm, speech therapy

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Model Description
Single case experimental design
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
6 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Gestures
Arm Type
Experimental
Arm Description
Use of hand gestures to improve speech rhythm and speech production
Arm Title
Auditory
Arm Type
Experimental
Arm Description
Use of auditory cues to improve speech rhythm and speech production
Intervention Type
Behavioral
Intervention Name(s)
Auditory
Intervention Description
Use of auditory cues to improve speech production
Intervention Type
Behavioral
Intervention Name(s)
Gestures
Intervention Description
Use of gestures to improve speech production
Primary Outcome Measure Information:
Title
Intelligibility
Description
Intelligibility = the accuracy with which a listener understands a speaker. It will be measured by having the subjects undergoing the therapy ("the talkers") read 28 phrases using accompanying gesture or auditory cues and listeners will transcribe the sentences. The number of words accurately transcribed / the number of words in the phrase = intelligibility score for each phrase per listener
Time Frame
immediately upon completion of the therapy
Secondary Outcome Measure Information:
Title
Ease of understanding
Description
Ease of understanding = the ease with which listeners understand the speakers. It will be measured by having the subjects undergoing the therapy ("the talkers") read 28 phrases using accompanying gesture or auditory cues and listeners will rate how easy it is to understand the talkers using a 0 to 9 visual analog scale with 0 = very easy and 9= very hard, for each phrase per listener
Time Frame
Immediately upon completion of the therapy
Title
Speech naturalness
Description
Speech naturalness = the degree to which the listeners consider the speakers to have natural or unnatural speech. It will be measured by having the subjects undergoing the therapy ("the talkers") read 28 phrases using accompanying gesture or auditory cues and listeners will rate how natural-sounding the talker sounds by using a 0 to 9 visual analog scale with 0 = very natural and 9 = very unnatural, for each phrase per listener
Time Frame
immediately upon completion of the therapy

10. Eligibility

Sex
All
Minimum Age & Unit of Time
21 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: diagnosis of idiopathic Parkinson's disease (4) or dysarthria secondary to ataxia (4) or healthy (4) monolingual speaker of American English (6) or native speaker of Spanish who speaks English with a Spanish accent (6) age 21 or older Exclusion Criteria: Cognitive impairment that prevents participation in the therapy Fluent speakers of languages other than English or Spanish younger than 21 years
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Alison Behrman, PhD
Organizational Affiliation
Lehman College
Official's Role
Principal Investigator
Facility Information:
Facility Name
Lehman College
City
Bronx
State/Province
New York
ZIP/Postal Code
10468
Country
United States

12. IPD Sharing Statement

Plan to Share IPD
Yes
IPD Sharing Plan Description
De-identified data will be shared with other researchers
IPD Sharing Time Frame
After completion of the study and publication of the data
IPD Sharing Access Criteria
Researchers who have contacted me directly with clear purpose and plan for use of data and then have IRB approval.

Learn more about this trial

Rhythmic Entrainment in Bilingual Speakers With Dysarthria

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