Robotic Assessments of Hand Function in Patients With Parkinson's Disease (RHK Parkinson)
Parkinson Disease
About this trial
This is an interventional other trial for Parkinson Disease focused on measuring Parkinson Disease, Sensory impairments, Kinaesthesia, Haptic perception, Robot-assisted assessments, Assessment of the hand sensory function
Eligibility Criteria
Ten patients with Parkinson's disease and 10 age-matched control subjects will be recruited.
Patients with Parkinson's disease: inclusion criteria
- Diagnosis of idiopathic Parkinson's disease according to UK Parkinson's disease society brain bank clinical diagnostic criteria
- Age between 35 and 80 years
- Hoehn and Yahr stage of I, II or III during the ON state
- Montreal Cognitive Assessment (MoCA) ≥ 26
No tremor, i.e.:
- Postural tremor for the hand: MDS-UPDRS 3.15 < 1
- Kinetic tremor of the hands: MDS-UPDRS 3.16 ≤ 1
- Rest tremor amplitude for the extremities: MDS-UPDRS 3.17 < 1
- Constancy of rest tremor: MDS-UPDRS 3.18 < 1
- The subject read, understood and signed the informed consent
Patients with Parkinson's disease: exclusion criteria
- Polyneuropathy registered in the anamnesis or peripheral sensory-motor impairments detected in a neurological clinical examination
- Mild to severe dyskinesia of the upper limbs: point 5 of the Abnormal Involuntary Movement Scale (AIMS) > 1
- Orthopedic pathologies of the upper limbs or other pathologies possibly interfering with the study
- Pacemaker, deep-brain-stimulator or other active implanted devices
Control subjects: inclusion criteria
- Age between 35 and 80 years
- Montreal Cognitive Assessment (MoCA) ≥ 26
- The subject read, understood and signed the informed consent
Control subjects: exclusion criteria
- Any history of neurological, orthopaedic or rheumatologic disease affecting the upper limbs or other pathologies possibly interfering with the study
- Pacemaker or other active implanted devices
Sites / Locations
- Clinica Hildebrand, Centro di Rehabilitazione Brissago
Arms of the Study
Arm 1
Experimental
Robotic assessment of sensory hand function
This arm involves a group of persons with Parkinson's disease and an age-matched control group. Both groups undergo the assessments of kinaesthesia and haptic perception of the hand implemented on the ReHapticKnob.