rTMS for Treatment of Pain and Craving
Pain, Chronic, Pain Acute
About this trial
This is an interventional treatment trial for Pain, Chronic focused on measuring treatment, brain stimulation
Eligibility Criteria
Inclusion Criteria:
- age 18-65
- currently prescribed prescription opiates for pain
Exclusion Criteria:
- documented history of seizures
- unstable chronic medical illness
- currently using any medications known to lower seizure risk
- metal above the waist
- pregnancy
- history of a negative reaction to TMS
Sites / Locations
- Medical University of South Carolina
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Placebo Comparator
Dorsolateral Prefrontal Cortex
Motor Cortex
Sham stimulation
Intervention: Real Transcranial Magnetic Stimulation Real Transcranial Magnetic Stimulation will be delivered to the left dorsolateral prefrontal cortex (10Hz, 110% of resting motor threshold) using a MagVenture MagPro B60 coil.
Intervention: Real Transcranial Magnetic Stimulation Real Transcranial Magnetic Stimulation will be delivered to the left primary motor cortex (10Hz, 80% of resting motor threshold) using a MagVenture MagPro B60 coil.
Intervention: Sham Transcranial Magnetic Stimulation Sham Transcranial Magnetic Stimulation will be delivered to the prefrontal cortex (10Hz, 110% of resting motor threshold) using the integrated sham system on the MagVenture MagPro B60 coil.