Study in Women With Metastatic Breast Cancer Whose Cancer Has Gotten Worse After Anthracycline and Taxane Therapy
Breast Neoplasms, Neoplasm Metastasis
About this trial
This is an interventional treatment trial for Breast Neoplasms
Eligibility Criteria
Inclusion Criteria: Locally advanced or metastatic breast cancer not amenable to surgery or radiation with curative intent Must have received any chemotherapy regimen in the past Evidence of tumor resistance to last chemotherapy defined as progression after 6 months of previous chemotherapy for advanced disease Must have measurable (by imaging techniques) disease Adequate bone marrow, liver and renal function Must provide evidence of informed consent and willingness and ability to comply with scheduled visits, treatment plan and study procedures. Exclusion Criteria: Received more than 2 prior chemotherapy regimens for metastatic disease Received in the past another drug of the same class as the investigational drug, i.e. topoisomerase I inhibitor Enrolled in another clinical intervention study Pregnancy, breast feeding, fertile women refusing to use reliable contraceptive methods Cardiac or thrombotic event in the last 12 months Brain metastases
Sites / Locations
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site
- Pfizer Investigational Site