Studying Electromyographic Activity in Patients With Upper Limb Amputations
Amputation, Traumatic
About this trial
This is an interventional basic science trial for Amputation, Traumatic
Eligibility Criteria
Inclusion criteria:
For the prosthetic control graft arm:
- Must have previously undergone upper limb amputation
- Must be otherwise healthy (e.g. no severe pain syndromes or untreated mental health disorders)
- Must be American Society of Anesthesiologists (ASA) Class I (low surgical risk)
- Must have sufficient soft tissue quality to support performance of the operative procedures
- Must have NOT previously received the partial muscle graft surgery
For the neuroma graft arm:
- Must have previously undergone upper limb amputation
- Must be otherwise healthy (e.g. no severe pain syndromes or untreated mental health disorders)
- Must have previously received the partial muscle graft surgery
For the able-bodied arm:
- Must have NOT undergone upper limb amputation
- Must be in good health
Exclusion criteria:
For the prosthetic control graft arm:
- Participants sustaining severe crushing or avulsion injuries with substantial superficial and deep scarring, may not be appropriate candidates for inclusion in the study
For the able-bodied arm:
- Participants with a history of nerve pain may not be appropriate candidates for inclusion in the study
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
Neuroma Graft
Prosthetic Control Graft
Able Bodied
In this arm, participants have already had partial muscle grafts placed on the amputated nerves to control neuroma growth. The investigators will place small electrodes percutaneously into the muscle grafts to record EMG signals and electrically stimulate the implanted nerves.
In this arm, participants will have an initial surgery to place partial muscle grafts on the amputated nerves. After a healing period, the investigators will place small electrodes percutaneously into the muscle grafts to record EMG signals and electrically stimulate the implanted nerves.
The investigators will place small electrodes percutaneously into intact muscles in the arm to record EMG signals and electrically stimulate the intact nerves nearby.