Time Restricted Feeding (4-hour Versus 6-hour) for Weight Loss in Obese Adults
Obesity, Diabetes
About this trial
This is an interventional prevention trial for Obesity
Eligibility Criteria
Inclusion Criteria:
- Male or female;
- body mass index (BMI) between 30.0 and 49.9 kg/m2;
- age between 18 and 65 years; sedentary (light exercise less than 1 h per week) or moderately active (moderate exercise 1 to 2 h per week);
- weight stable for >3 months prior to the beginning of the study (gain or loss <4 kg);
- able to give written informed consent
Exclusion Criteria:
- Smoker; diabetic;
- taking weight loss medications;
- taking medication that requires eating food before (or with) the medication; history of eating disorders;
- night-shift workers;
- perimenopausal;
- pregnant women
Sites / Locations
- University of Illinois Chicago
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
No Intervention
Experimental
4-hour Time restricted feeding
Control
6-hour Time restricted feeding
4-h TRF subjects will consume food ad libitum between 3pm and 7pm (4-h feeding window), and refrain from eating and drinking caloric beverages from 7pm to 3pm (20-h fasting window) each day. These subjects will not be instructed to limit/monitor energy intake during the feeding window. Subjects will be encouraged to drink plenty of water during the fasting period.
Controls will be instructed to maintain their weight throughout the trial, and not to change eating or physical activity habits. Controls will visit the research center at the same frequency as the TRF groups (for outcome measurements).
6-h TRF subjects will consume food ad libitum between 1pm and 7pm (6-h feeding window), and refrain from eating and drinking caloric beverages from 7pm to 1pm (18-h fasting window) each day. These subjects will not be instructed to limit/monitor energy intake during the feeding window. Subjects will be encouraged to drink plenty of water during the fasting period.