Transcranial Direct/ Alternating Current Stimulation for Parkinson's Disease Treatment
Parkinson Disease, tACS, tDCS
About this trial
This is an interventional treatment trial for Parkinson Disease
Eligibility Criteria
Inclusion Criteria: diagnosis of idiopathic PD according to the movement disorder society criteria right-handed no clinically known hearing or vision impairment no history of epilepsy, dementia, other brain disorders apart from PD, severe internal organs disease, age-related frailty, etc. Exclusion Criteria: parkinsonism due to drugs, Cerebrovascular disease, encephalitis, poisoning, traumatic brain injury, etc. Metal implants in the head (i.e., deep brain stimulator or aneurysm clips) severe somatic or psychiatric disorders that require medication or routinely monitoring participated in other interventional studies within the past 3 months
Sites / Locations
- Anhui Medical University
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Sham Comparator
Transcranial Alternating Current Stimulation
Transcranial Direct Current Stimulation
Sham Group with No Actual Stimulation
the alternating current stimulation lasted 20 mins and was delivered at 2mA (peak to peak) at 20Hz during the Simple Reaction Task(SRT), targeting the primary motor cortex. EEG should be acquired before and after the stimulation session.
the direct current stimulation lasted 20 minutes and was delivered at 2mA during the SRT, targeting at the primary motor cortex. EEG should be acquired before and after the stimulation session.
the procedure of this protocol lasted 20 minutes and was delivered at 0mA during the SRT. EEG should be acquired before and after the stimulation session.