Use of MCT Oil for Enhancement of Weight Loss and Glycemic Control in Obese Diabetic Patients
Obesity, Type 2 Diabetes Mellitus
About this trial
This is an interventional treatment trial for Obesity focused on measuring Weight loss, MCT oil hypocaloric liquid diet, LCT oil hypocaloric liquid diet, Gastric Bypass
Eligibility Criteria
Inclusion Criteria: Patient of the Nutrition and Weight Management Center at Boston Medical Center Obese ( BMI equal or greater to 30 kg/m2 Men and women Age more than or equal to 18 years Type 2 diabetes mellitus controlled by diet or use of Metformin or Impaired fasting glucose (FBS more than or equal to 100 mg/dl) Only diet-controlled diabetics or those on Metformin will be considered since all classes of anti-diabetic agents have different effects on appetite and body weight, which may confound the interpretation of study results. Exclusion Criteria: Currently not a patient at the Nutrition and Weight Management Center at Boston Medical Center Need for oral anti-diabetic agents (other than Metformin) Abnormal thyroid status: hyperthyroidism or hypothyroidism (TSH less than 0.5 or more than 5.0) Significant liver disease (bilirubin more than or equal to 2.0 or liver enzyme more than 3 times upper limited of normal range) Significant renal disease (creatinine more than or equal to 2.0) On the following medications known to affect carbohydrate and lipid metabolism: steroids, Beta adrenergic blockers, diuretics, insulin, and hypolipidemic agents Use of prescription or over the counter weight loss medications Weight loss of >5% or more in the last three (3) months Anorexia nervosa or bulimia nervosa Pregnancy or lactation Significant lactose intolerance Significant egg allergy History of drug or alcohol addiction.
Sites / Locations
- Boston University Medical Center
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
1
2
Will receive MCT study oil to supplement into liquid meal replacements.
Will receive LCT oil to supplement into their liquid meal replacements.