search
Back to results

VLDL-triglyceride Under Acute Hyperinsulinaemia

Primary Purpose

Obesity

Status
Completed
Phase
Locations
Denmark
Study Type
Observational
Intervention
Food (fat free meal)
Sponsored by
University of Aarhus
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an observational trial for Obesity focused on measuring VLDL, Kinetics, Hyperinsulinaemia, Obesity

Eligibility Criteria

20 Years - 65 Years (Adult, Older Adult)MaleAccepts Healthy Volunteers

Inclusion Criteria:

- Written consent

Exclusion Criteria:

  • Known diseases
  • Alcohol abuse
  • Smoker
  • Regular use of medicine

Sites / Locations

  • Department of Endocrinology M, Aarhus Hospital

Arms of the Study

Arm 1

Arm 2

Arm Type

Arm Label

1

2

Arm Description

Lean male

Males with type 2 diabetes

Outcomes

Primary Outcome Measures

VLDL metabolism

Secondary Outcome Measures

Full Information

First Posted
February 18, 2008
Last Updated
November 4, 2011
Sponsor
University of Aarhus
search

1. Study Identification

Unique Protocol Identification Number
NCT00624104
Brief Title
VLDL-triglyceride Under Acute Hyperinsulinaemia
Official Title
VLDL-triglyceride Under Acute Hyperinsulinaemia
Study Type
Observational

2. Study Status

Record Verification Date
November 2011
Overall Recruitment Status
Completed
Study Start Date
March 2008 (undefined)
Primary Completion Date
December 2010 (Actual)
Study Completion Date
December 2010 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University of Aarhus

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of the study is to investigate and compare the lipid metabolism in lean and obese individuals. We want to investigate the effect of postprandial hyperinsulinaemia on VLDL-triglyceride metabolism

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity
Keywords
VLDL, Kinetics, Hyperinsulinaemia, Obesity

7. Study Design

Enrollment
16 (Actual)
Biospecimen Retention
Samples With DNA
Biospecimen Description
specimen of muscle specimen of adipose tissue

8. Arms, Groups, and Interventions

Arm Title
1
Arm Description
Lean male
Arm Title
2
Arm Description
Males with type 2 diabetes
Intervention Type
Dietary Supplement
Intervention Name(s)
Food (fat free meal)
Intervention Description
Fat free meal (40% of REE)
Primary Outcome Measure Information:
Title
VLDL metabolism
Time Frame
Few hours

10. Eligibility

Sex
Male
Minimum Age & Unit of Time
20 Years
Maximum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: - Written consent Exclusion Criteria: Known diseases Alcohol abuse Smoker Regular use of medicine
Study Population Description
Males with diabetes from departments out-patient clinic. Control group of healthyt volunteers
Sampling Method
Non-Probability Sample
Facility Information:
Facility Name
Department of Endocrinology M, Aarhus Hospital
City
Aarhus C
ZIP/Postal Code
8000
Country
Denmark

12. IPD Sharing Statement

Learn more about this trial

VLDL-triglyceride Under Acute Hyperinsulinaemia

We'll reach out to this number within 24 hrs