Weight Loss and Changes in Cardiovascular Risk Markers With a Low Glycemic Diet Compared With a Standard Diet
Obesity, Metabolic Syndrome
About this trial
This is an interventional prevention trial for Obesity focused on measuring Obesity,, weight loss,, diet counseling, low-glycemic load
Eligibility Criteria
Inclusion Criteria: Men or women age 30-65, BMI in the range 28-35 kg/m2 for women and 28-40kg/m2 for men. At least one of the following components of the metabolic syndrome; fasting triglycerides > 1,7, fasting glucose 6,0-6,9, HDL-cholesterol <1,03 (males) or <1,29 (females), Blood pressure >130/85 (with or without treatment), diet-treated diabetes mellitus or drug treated hypertension. Stable weight range of 4 kg or less the last 12 weeks, No major change in physical activity the last 12 weeks Exclusion Criteria: Any symptomatic cardiovascular disease Diabetes requiring drug treatment Currently on special diet Hepatic/renal dysfunction Hypothyroidism (unstable) GI disorder impairing compliance with diet recommendation, History of unstable psychiatric or medical disorder, Need of lipid lowering drug, Alcohol or drug abuse, Participation in drug trial the last 30 days, Use of drugs for weight reduction last 12 weeks, pregnancy or planned pregnancy, Obesity of known endocrine origin, history of obesity surgery, Uncontrolled hypertension (>160/100), Previous participation in >3 weight reduction programs, or within last 12 months, Not willing to be randomized, Individual judged to be unable to follow instructions and procedures of the study
Sites / Locations
- Ulleval University Hospital, dep. of preventive cardiology